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EC number: 226-364-2 | CAS number: 5372-81-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1995
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study performed according to current OECD-Guideline and GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 995
- Report date:
- 1995
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Dimethyl 2-aminoterephthalate
- EC Number:
- 226-364-2
- EC Name:
- Dimethyl 2-aminoterephthalate
- Cas Number:
- 5372-81-6
- Molecular formula:
- C10H11NO4
- IUPAC Name:
- 1,4-dimethyl 2-aminobenzene-1,4-dicarboxylate
- Reference substance name:
- dimethyl-2-aminoterephthalate
- IUPAC Name:
- dimethyl-2-aminoterephthalate
- Details on test material:
- purity: > 99.9 % (m/m)
no stock solution was prepared. Due to the low solubility of the material the test item was directly weight into the testing tubes.
Constituent 1
Constituent 2
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - source of inoculum: municipal treatment plant Frankfurt-Sindlingen, Germany
- Preparation of inoculum for exposure: The activated sludge was centrifuged, sediment of activated sludge was washed, centrifuged and resuspended. The sludge was 7 days pre-ventilated to get rid of all C.
- Initial cell/bimass concentration: 10 ml/l activated suldge suspension with 16 g/l of centrifuged sediment. The dry mass of the suspension was 1,9 g/l. - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 63.75 mg/L
- Based on:
- test mat.
- Initial conc.:
- 67 mg/L
- Based on:
- test mat.
- Initial conc.:
- 65 mg/L
- Based on:
- test mat.
- Initial conc.:
- 63.5 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- < 20
- Sampling time:
- 28 d
- Details on results:
- The mean value of 4 tests in parallel was below 20 %. Therefore no graphic was produced.
The depletion of the reference substance showed an O2-reduction of > 60% witin 10 days. The O2-consumption of blind controls was < 60 mg/l (O2).
There was no significant biological degradation of the test item shown. The O2-consumtopn witin th test period of 28 d was below 20 % of theoretical maxium.
BOD5 / COD results
BOD5 / COD
- Parameter:
- COD
- Value:
- 8.7 other: mg O2/l
- Results with reference substance:
- The depletion of the reference substance showed an O2-reduction of > 60% witin 10 days. The O2-consumption of blind controls was < 60 mg/l (O2).
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- The degradation rate was below 20 % after 28 d. The product is not readily biodegradable.
- Executive summary:
The degradation rate was below 20 % after 28 d. The product is not readily biodegradable.
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