Registration Dossier
Registration Dossier
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EC number: 202-548-8 | CAS number: 96-97-9
Endpoint summary
Administrative data
Description of key information
Additional information
Biodegradation in water :
No. of studies of target substance 5-nitrosalicylic acid reviewed for Biodegradation in water: screening tests from reliable sources having Klimisch rating 2.
The summary of the results are presented below
Sr.No |
Endpoint |
Half life |
Parameter |
Sources |
1 |
ready biodegradability |
50% degradation in 15 days |
Test mat. analysis |
Predicted data from PBT profiler |
2 |
ready biodegradability |
51.66% degradation |
O2 consumption |
Predicted data from QSAR |
By applying weight of evidence approach the target chemical found to be readily biodegradable with 50% to 51.66% percentage degradation.Thus it is concluded that 5-nitrosalicylic acid is biodegradable in water.
Biodegradation in water and sediment :
Based on the Level III Fugacity Model, the half life period of the 5-nitrosalicylic acid was estimated. The half period of 5-nitrosalicylic acid in water is 15 days (360 hrs) therefore it is considered that the substance will qualify as not persistent as the half life does not exceed the EPA criteria of 60 days. So, it can be confirmed that the substance is readily biodegradable in water medium where as in sediment the half life is 140 days (3360 hrs).
Based on this value, it can be inferred that the substance is persistent in sediment medium and is not readily biodegradable probably due to the anaerobic conditions existing in most sediments. However, it can be observed that 5-nitrosalicylic acid does not diffuse in the sediment medium since it's percentage in the sediment medium is reported to be 0% and hence persistence in the sediment compartment is not likely to be critical.
Media |
Half-Life (days) |
Percent in |
Water |
15 |
24% |
Sediment |
140 |
0% |
Biodegradation in soil :
No. of studies of target substance 5-nitrosalicylic acid reviewed for Biodegradation in soil from reliable sources having Klimisch rating 2.
The summary of the results are presented below
Sr.No |
Endpoint |
Half life |
Parameter |
result |
Sources |
1 |
ready biodegradability |
30days |
Test mat. analysis |
biodegradable |
Predicted data from PBT profiler and EPI suite |
2 |
ready biodegradability |
28.399 days |
DT50(Dissipation time) |
biodegradable |
Predicted data from QSAR |
By applying weight of evidence approach the target chemical found to be readily biodegradable with half life 28.399 to 30 days. does not exceeds the threshold (60 days) of being persistent in soil Thus it is concluded that 5-nitrosalicylic acid is biodegradable in soil.
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