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Diss Factsheets
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EC number: 420-380-5 | CAS number: 136465-81-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 31st August 1995
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Comparable to guideline study with acceptable restrictions. This study was performed in compliance with the GLP regulations. Only memorandum available; no full study report.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 995
- Report date:
- 1995
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Deviations:
- not specified
- Principles of method if other than guideline:
- No further details were provided.
- GLP compliance:
- yes
Test material
- Reference substance name:
- PTH-decahydroamide
- IUPAC Name:
- PTH-decahydroamide
- Reference substance name:
- Ro 31-9373/000
- IUPAC Name:
- Ro 31-9373/000
- Details on test material:
- No further details were provided.
Constituent 1
Constituent 2
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No further details were provided.
Sampling and analysis
- Analytical monitoring:
- not specified
- Details on sampling:
- No further details were provided.
Test solutions
- Vehicle:
- not specified
- Details on test solutions:
- No further details were provided.
Test organisms
- Test organisms (species):
- activated sludge
- Details on inoculum:
- No further details were provided.
Study design
- Test type:
- not specified
- Water media type:
- not specified
- Remarks on exposure duration:
- No further details were provided.
- Post exposure observation period:
- No further details were provided.
Test conditions
- Hardness:
- No further details were provided.
- Test temperature:
- No further details were provided.
- pH:
- No further details were provided.
- Dissolved oxygen:
- No further details were provided.
- Salinity:
- No further details were provided.
- Nominal and measured concentrations:
- No further details were provided.
- Details on test conditions:
- No further details were provided.
- Reference substance (positive control):
- not specified
Results and discussion
- Details on results:
- No significant inhibition in respiration rate of the sludge (> 10 %) was recorded at 100 mg PTH-decahydroamide (Ro 31-9373/000) per litre.
- Results with reference substance (positive control):
- No further details were provided.
- Reported statistics and error estimates:
- No further details were provided.
Any other information on results incl. tables
No further details were provided.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- No significant inhibition in respiration rate of the sludge (> 10 %) was recorded at 100 mg PTH-decahydroamide (Ro 31-9373/000) per litre. Thus under the conditions of the test PTH-decahydroamide (Ro 31-9373/ 000) was not toxic to waste water bacteria.
- Executive summary:
The study procedure described was performed on the basis of EC directive 87/302/EEC, Part C (adopted 1988) and OECD guideline No. 209 (1984). No significant inhibition in respiration rate of the sludge (> 10 %) was recorded at 100 mg PTH-decahydroamide (Ro 31-9373/000) per litre. Thus under the conditions of the test PTH-decahydroamide (Ro 31-9373/ 000) was not toxic to waste water bacteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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