Registration Dossier
Registration Dossier
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EC number: 205-736-8 | CAS number: 149-30-4
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: A scientific publication.
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 989
Materials and methods
- Principles of method if other than guideline:
- Dermal absorption of radiolabelled dose.
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-Mercaptobenzothiazole
- IUPAC Name:
- 2-Mercaptobenzothiazole
- Reference substance name:
- Benzothiazole-2-thiol
- EC Number:
- 205-736-8
- EC Name:
- Benzothiazole-2-thiol
- Cas Number:
- 149-30-4
- Molecular formula:
- C7H5NS2
- IUPAC Name:
- 1,3-benzothiazole-2-thiol
Constituent 1
Constituent 2
- Radiolabelling:
- yes
Test animals
- Species:
- guinea pig
- Strain:
- not specified
- Sex:
- female
Administration / exposure
- Type of coverage:
- occlusive
- Duration of exposure:
- 96h
Results and discussion
Any other information on results incl. tables
Guinea pigs absorbed 33.4% of topical radiolabelled dose.
Applicant's summary and conclusion
- Conclusions:
- Guinea pigs absorbed 33.4% of topical radiolabelled dose.
- Executive summary:
The study results shows that Guinea pigs absorbed 33.4% of topical radiolabelled dose.
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