p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide

Flammability

Administrative data

Endpoint:

flammability

Remarks:

Pyrophoric liquids/solids (migrated from section 'Flammability')

Type of information:

experimental study

Adequacy of study:

key study

Study period:

15.05.2002

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: The study was conducted by a well experienced research laboratory and in accordance with several internationally acknowledged guidelines.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2002

Report date:

2002

Materials and methods

Test guideline

Guideline:

other:

Principles of method if other than guideline:

Equipment.
The equipment used is constituted for an explosion reactor, a previous heater that enable to operate with the comburent mixture at the desired emperature and for a flow measure and mixer system for the sample gassy mixture preparation with known oxygen content. Complete the
equipment, the violence explosion measure device, which are analysed by gassy atmosphere control.
The reactor (volume = 2,3 l) is constituted for a stainless steel cylinder closed at the inferior extremity by a metallic base with cup shape that enable to content the powder and facilitate the dispersion; the reactor superior extremity is closed by a diaphragm with ventilation disc function.
A heater so as to operate at the desired temperature rolls up the reactor.
The comburent atmosphere is stored in a pressure deposit controlled by a solenoid valve and is feed to the reactor over a device that distribute the way that an efficient powder dispersion in the comburent is obtained.
The powder-air cloud is ignited by means of a metallic spiral Iead to the incandescence by a feeding system !hat supply at the beginning a tension
enable to bring the line to the incipient fusion and successively a tension to maintain that state.
The pressure observed by the measure chain constituted by a pressure transductor, the computer !hat permit the eventual register elaboration.
Procedure:
The quantity of dust predetermined is placed at the bottom of the reactor, the comburent is sent putting on the electrovalve. When the comburent
atmosphere alimentation takes place in the reactor the spark is provided to the dispersion powder-air that is hardly constituted.
The pressure increment, following an explosive phenomenon, is observed through the pressure transductor attached by means of the charge
amplificator to the data acquisition.
The mixture in which, on statistics base, a flame that is initiated in the ignition source and it is spread in the reactor volume or anyway generates a
pressure increase is considerate flammable (this term is synonym of explosivity). The sample of examination is considerate inflammable if all the
mixture with a powder concentration of at least 2000 mg/l don't give rise to flame propagation or pressure increment.

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide

EC Number:

251-529-0

EC Name:

p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide

Cas Number:

33456-68-7

Molecular formula:

C20H22N2O5S

IUPAC Name:

4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzene-1-sulfonamide

Results and discussion

Pyrophoric solids

Test procedure:

ignition time on contact with air

Remarks:

Ignition on contact with air refers to either Pyrophoric solids or Pyrophoric liquids depending on physical state (migrated information).

Remarks on result:

ignition on contact with air (not further specified)

Remarks:

corresponding to 'yes' in migrated source record.| Remarks: | Additional remarks: Lowest Flammability Limit: 800 mg/l.

Pyrophoric liquids

Test procedure:

ignition time on contact with air

Remarks:

Ignition on contact with air refers to either Pyrophoric solids or Pyrophoric liquids depending on physical state (migrated information).

Remarks on result:

ignition on contact with air (not further specified)

Remarks:

corresponding to 'yes' in migrated source record.| Remarks: | Additional remarks: Lowest Flammability Limit: 800 mg/l.

Any other information on results incl. tables

Lower Limit of flammability:

The lower Limit of inflammability of the sample examined, has been obtained by direct powder dispersion in the air in the equipment of the experiment, under ambient temperature and atmospheric pressure, is represented in the following table.

Sample	Li [mg/l]
ARDF 26 Fase X	800

Applicant's summary and conclusion

Conclusions:

ARDF 26 Fase X, can be considered lightly flammable, if its lowest Iimit of flammability, its non explosive behaviour and its MIE upper than 1000 mJ
are taking into account.