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EC number: 412-770-9 | CAS number: 12141-67-2 NATRIUMMETAWOLFRAMAT
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 84/449/EC, B.1
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- Hexasodium tungstate hydrate
- EC Number:
- 412-770-9
- EC Name:
- Hexasodium tungstate hydrate
- Cas Number:
- 12141-67-2
- Molecular formula:
- Na6 H2 W12 O40 . xH2O
- IUPAC Name:
- hydrate hydrogen oxygen sodium hydride tungsten
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- water
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 1 715 mg/kg bw
- Based on:
- test mat.
- Mortality:
- Male: 5000 mg/kg bw; Number of animals: 5; Number of deaths: 5
Male: 2800 mg/kg bw; Number of animals: 5; Number of deaths: 5
Male: 1580 mg/kg bw; Number of animals: 5; Number of deaths: 1
Female: 5000 mg/kg bw; Number of animals: 5; Number of deaths: 5
Female: 2800 mg/kg bw; Number of animals: 5; Number of deaths: 5
Female: 1580 mg/kg bw; Number of animals: 5; Number of deaths: 2 - Clinical signs:
- other: Signs of toxicity related to dose levels: 5000 mg/kg: Lethargy, hunched posture and tachypnoea 2800 mg/kg: Lethargy, piloerection, ataxia and pale skin 1580 mg/kg: Lethargy, piloerection and hunched posture Although some of the animals that died showed s
- Gross pathology:
- Effects on organs:
5000 mg/kg: Haemorrhages in the glandular stomach, glandular stomach dark red, lungs dark red, swollen intestine.
2800 mg/kg: haemorrhages in the glandular stomach or lungs, lungs and glandular stomach red in colour, pale liver, pale kidneys, pale lungs, bloody liquid inthe urinary bladder.
1580 mg/kg: Pale liver, pale kidneys, red lungs
Applicant's summary and conclusion
- Interpretation of results:
- harmful
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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