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EC number: 605-637-3 | CAS number: 172529-93-0
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17.09.2007 - 25.10.2007
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- 1,3-dimethyl 2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]propanedioate
- Cas Number:
- 172529-93-0
- Molecular formula:
- C12 H14 Cl N5 O4
- IUPAC Name:
- 1,3-dimethyl 2-[2-(2-amino-6-chloro-9H-purin-9-yl)ethyl]propanedioate
- Reference substance name:
- 2-Amino-6-chloro-9-(methyl-2-carbomethoxybutanoate-4- yl)purine.
- IUPAC Name:
- 2-Amino-6-chloro-9-(methyl-2-carbomethoxybutanoate-4- yl)purine.
- Details on test material:
- Formula: C12H14ClN5O4
Appearance: White to pale yellow solid
Expiry date: 31 December 2007
Constituent 1
Constituent 2
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 15 mg/L
- Based on:
- other: Nominal carbon concentration
Reference substance
- Reference substance:
- other: sodium benzoate
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 26.7
- Sampling time:
- 28 d
- Details on results:
- Points of degradation plot (test substance):
4.1 % degradation after 4 d
12.5 % degradation after 10 d
14.3 % degradation after 15 d
26.7 % degradation after 28 d
BOD5 / COD results
- Results with reference substance:
- Points of degradation plot (reference substance):
41.8 % degradation after 4 d
73.2 % degradation after 10 d
78.7 % degradation after 15 d
95.2 % degradation after 28 d
Any other information on results incl. tables
The reference substance sodium benzoate was degraded by 73.2 % within 10 days.
Degradation in the toxicity control, which contained sodium benzoate and the test substance, was not indicative of an inhibition of the microbial activity by the test substance.
The biodegradation of "Fam-stage-1" with a nominal concentration of 15 mg carbon/L reached 26.7 % after 28 days of incubation at 22.7 ± 0.3 °C.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- According to the results of this study, "Fam-stage-1" cannot be classified as readily biodegradable.
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