Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Available data in the IUCLID Chemical Data Sheet; the data have not undergone any evaluation by the European Commission. It's not known if the study was performed under GLP. The method is not known.

Data source

Reference
Reference Type:
grey literature
Title:
IUCLID data set
Author:
European Commission
Year:
2000
Bibliographic source:
http://esis.jrc.ec.europa.eu/
Report date:
2000

Materials and methods

Principles of method if other than guideline:
Method not available
GLP compliance:
not specified
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
3,4-dichloro-α,α,α-trifluorotoluene
EC Number:
206-337-1
EC Name:
3,4-dichloro-α,α,α-trifluorotoluene
Cas Number:
328-84-7
Molecular formula:
C7H3Cl2F3
IUPAC Name:
1,2-dichloro-4-(trifluoromethyl)benzene

Results and discussion

Test results
Species / strain:
not specified
Metabolic activation:
not specified
Genotoxicity:
negative
Cytotoxicity / choice of top concentrations:
not specified
Vehicle controls validity:
not specified
Untreated negative controls validity:
not specified
Positive controls validity:
not specified
Remarks on result:
other: all strains/cell types tested
Remarks:
Migrated from field 'Test system'.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
negative