Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 601-809-7 | CAS number: 12182-76-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Carcinogenicity
Administrative data
Description of key information
Calculations of the carcinogenic potential and carcinogenicity are based on the structure of yttrium chromite. The results from structural alerts indicate that yttrium chromite has no carcinogenic effects.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Link to relevant study records
- Endpoint:
- carcinogenicity
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Values are predicted from model. Thus, they provide an approximation compared to experimental measure.
- Principles of method if other than guideline:
- The following models were applied to examine for structural alerts that indicate the carcinogenic potential of yttrium chromite using ChemProp:
Carcinogenic potential
Carcinogenicity by Benigni et al.
Consensus model (Probability for carcinogenicity & weight of evidence for carcinogenicity). The Consensus model combines the output of the individual models that can be used by ChemProp. The lowest possible value is obtained when no model predicts an effect, and the highest possible (0.86) value when all models predict the effect. - Details on results:
- Carcinogenic potential (1=active; 0= inactive): 0 - Be aware: No model domain is known!
Carcinogenicity by Benigni et al. (1=active; 0= inactive): 0
Probability for carcinogenicity (0.26 ... 0.86): 0.26
Weight of evidence for carcinogenicity (-4.6 ... 7.9): -4.6 - Conclusions:
- Calculations of the carcinogenic potential and carcinogenicity were undertaken for yttrium chromite. The calculations are based on the structure of yttrium chromite. The results show that yttrium chromite has no carcinogenic effects.
- Executive summary:
We tested for structural alerts and potential for carcinogenicity of yttrium chromite. The estimation is based on various models including the potential of carcinogenicity, the model by Benigni et al. well as the Consensus model , using ChemProp. The potential of carcinogenicity and the carcinogenicity by Benigni et al. are both 0 (1=active; 0= inactive). The results of the Consensus model predict the lowest possible values for probability for carcinogenicity and the weight of evidence of the model. Therefore, we can consider that yttrium chromite has no carcinogenic effects.
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available (further information necessary)
Carcinogenicity: via inhalation route
Link to relevant study records
- Endpoint:
- carcinogenicity
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Values are predicted from model. Thus, they provide an approximation compared to experimental measure.
- Principles of method if other than guideline:
- The following models were applied to examine for structural alerts that indicate the carcinogenic potential of yttrium chromite using ChemProp:
Carcinogenic potential
Carcinogenicity by Benigni et al.
Consensus model (Probability for carcinogenicity & weight of evidence for carcinogenicity). The Consensus model combines the output of the individual models that can be used by ChemProp. The lowest possible value is obtained when no model predicts an effect, and the highest possible (0.86) value when all models predict the effect. - Details on results:
- Carcinogenic potential (1=active; 0= inactive): 0 - Be aware: No model domain is known!
Carcinogenicity by Benigni et al. (1=active; 0= inactive): 0
Probability for carcinogenicity (0.26 ... 0.86): 0.26
Weight of evidence for carcinogenicity (-4.6 ... 7.9): -4.6 - Conclusions:
- Calculations of the carcinogenic potential and carcinogenicity were undertaken for yttrium chromite. The calculations are based on the structure of yttrium chromite. The results show that yttrium chromite has no carcinogenic effects.
- Executive summary:
We tested for structural alerts and potential for carcinogenicity of yttrium chromite. The estimation is based on various models including the potential of carcinogenicity, the model by Benigni et al. well as the Consensus model , using ChemProp. The potential of carcinogenicity and the carcinogenicity by Benigni et al. are both 0 (1=active; 0= inactive). The results of the Consensus model predict the lowest possible values for probability for carcinogenicity and the weight of evidence of the model. Therefore, we can consider that yttrium chromite has no carcinogenic effects.
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available (further information necessary)
Carcinogenicity: via dermal route
Link to relevant study records
- Endpoint:
- carcinogenicity
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Values are predicted from model. Thus, they provide an approximation compared to experimental measure.
- Principles of method if other than guideline:
- The following models were applied to examine for structural alerts that indicate the carcinogenic potential of yttrium chromite using ChemProp:
Carcinogenic potential
Carcinogenicity by Benigni et al.
Consensus model (Probability for carcinogenicity & weight of evidence for carcinogenicity). The Consensus model combines the output of the individual models that can be used by ChemProp. The lowest possible value is obtained when no model predicts an effect, and the highest possible (0.86) value when all models predict the effect. - Details on results:
- Carcinogenic potential (1=active; 0= inactive): 0 - Be aware: No model domain is known!
Carcinogenicity by Benigni et al. (1=active; 0= inactive): 0
Probability for carcinogenicity (0.26 ... 0.86): 0.26
Weight of evidence for carcinogenicity (-4.6 ... 7.9): -4.6 - Conclusions:
- Calculations of the carcinogenic potential and carcinogenicity were undertaken for yttrium chromite. The calculations are based on the structure of yttrium chromite. The results show that yttrium chromite has no carcinogenic effects.
- Executive summary:
We tested for structural alerts and potential for carcinogenicity of yttrium chromite. The estimation is based on various models including the potential of carcinogenicity, the model by Benigni et al. well as the Consensus model , using ChemProp. The potential of carcinogenicity and the carcinogenicity by Benigni et al. are both 0 (1=active; 0= inactive). The results of the Consensus model predict the lowest possible values for probability for carcinogenicity and the weight of evidence of the model. Therefore, we can consider that yttrium chromite has no carcinogenic effects.
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available (further information necessary)
Justification for classification or non-classification
There is no indication for carcinogenic potential of yttrium chromite, so that the substance is not classified for carcinogenicity.
Additional information
We tested for structural alerts and potential for carcinogenicity of yttrium chromite. The estimation is based on various models including the potential of carcinogenicity, the model by Benigni et al. well as the Consensus model , using ChemProp. The potential of carcinogenicity and the carcinogenicity by Benigni et al. are both 0 (1=active; 0= inactive). The results of the Consensus model predict the lowest possible values for probability for carcinogenicity and the weight of evidence of the model. Therefore, we can consider that yttrium chromite has no carcinogenic effects.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.