Registration Dossier
Registration Dossier
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EC number: 232-227-8 | CAS number: 7790-86-5
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The key study of Peither (2011), in which cerium was added as Ce(NO3)3, yielded a 96-h LC50 of 0.13 mg Ce/L for juvenile rainbow trout. This value corresponds to a 96-h LC50 of 0.23 mg CeCl3/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.13 mg/L
Additional information
Three relevant studies are available on the acute toxicity of cerium to fish. The key study of Peither (2011) exposed juvenile rainbow trout for 96 h to Ce(NO3)3. Based on measured dissolved cerium concentrations, a 96-h LC50 of 0.13 mg Ce/L was obtained (corresponding to a 96-h LC50 of 0.3 mg Ce(NO3)3/L and 0.23 mg CeCl3/L).
The study of Gard (1990) also exposed juvenile rainbow trout to Ce(NO3)3, however, the study was finished after 24 h of exposure. The 24-h LC50 was 0.77 mg Ce/L, based on nominal concentrations. Although no analytical verification of test concentrations was performed, the study is considered as a supporting study because the LC50 is more or less in agreement with that of the key study of Peither (2011).
Finally, the third study of Bazin (1996), which also used Ce(NO3)3 for dosing purposes, reported a 96-h LC50 for juvenile rainbow trout of 5.59 mg Ce/L, which is considerably higher than the results of the other two studies. The results of this study are not considered reliable because no analytical verification of test concentrations was performed, which most likely resulted in an underestimation of toxicity. The results of this study were therefore disregarded.
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