1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, hydrochloride (1:2), (2S)-

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

other: Guideline UN N.1

Deviations:

no

GLP compliance:

no

Test procedure:

burning time (test type not further specified)

Remarks:

or specified in description of method (migrated information)

Burning time:

> 45 s

In the preliminary experiment (200 mm distance), the test substance melted and burned after the ignition source has been removed less than 1 second independently and still terminated within the delay line. Further tests were not necessary.

Interpretation of results:

non flammable

Remarks:

Migrated information

Conclusions:

1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- did not burn down or burn up.

Executive summary:

1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- melted when approached by the ignition flame (in accordance with the guideline UN N.1) and did not burn down or burn up, indicating that the substance is not flammable.

Reference 2

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

EU Method A.12 (Flammability (Contact with Water))

Deviations:

no

GLP compliance:

no

Remarks on result:

no reaction with water observed

RESULTS: - There was no evolution of gas in dangerous quantities (¿ 1L/kg*h) detected
-The maximum gas evolution rate was 0.2 L/kg*h
-A self-ignition of the gases in contact with water has not been observed

Interpretation of results:

other: does not emit flammable gases in contact with water

Conclusions:

In accordance with section 1 of REACH Annex XI, a study on flammability in contact with water does not need to be conducted as the substance does not emit flammable gases in contact with water. Based on the structure the substance does not contain metals or metalloids.

Executive summary:

The flammability of a substance on contact with water is determined following the methods N.5 (UN-Manual of testing) or A.12 (EU-method).

However, in accordance with section 1 of REACH Annex XI, a study on flammability in contact with water does not need to be conducted as the substance does not emit flammable gases in contact with water. Based on the structure the substance does not contain metals or metalloids.

Reference 3

Endpoint:

pyrophoric solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied

Description of key information

A) Flammability: not flammable solid
B) Contact with water: In accordance with section 1.5 of REACH Annex XI, the study does not need to be performed as no reactivity with water is expected due to the chemical structure.
C) Pyrophoric properties: In accordance with section 1.5 of REACH Annex XI, the study does not need to be performed as no
pyrophoric properties are expected due to the chemical structure.

Key value for chemical safety assessment

Flammability:

non flammable

Justification for classification or non-classification

The substance is not readily combustible, has no pyrophoric property, and shows no flammability in contact with water; and hence no

classification according to both Directive 67/548/EEC and GHS (Regulation EC 1272/2008).