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EC number: 248-502-0 | CAS number: 27503-81-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because a long-term aquatic toxicity study on invertebrates is available
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Study period:
- from Oct. 05, 1989 to Oct. 23, 1989
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- significant methodological deficiencies
- Remarks:
- Old OECD 202 guideline test with GLP, but the exposure period is only 24h, and the determination of the stability, homogenity, and concentration of the test material in the test medium was not reported.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- yes
- Remarks:
- only 24h test duration
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Details on sampling:
- no data
- Vehicle:
- no
- Details on test solutions:
- Preparation of test medium: stock solution (1100 mg/L)
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Species: Daphnia magna Straus parthenogenetic females
Basic strain: clone-breed of the Federal Board of Health; Berlin
Test animals: laboratory-bred by Bayer AG Leverkusen
Age of the animals: 6 - 24 hours - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 24 h
- Hardness:
- no data
- Test temperature:
- 19.3 °C
- pH:
- 8.0 - 8.1
- Dissolved oxygen:
- 8.7 mg/L
- Salinity:
- no data
- Nominal and measured concentrations:
- nominal: 707 mg/L, 1000 mg/L
- Details on test conditions:
- Number of duplicate determinations: 2
Test volume: 20 mL
Number of daphnias per test vessel: 10 - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Key result
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- Both of the immobility values at the two test concentrations (707 mg/l and 1000 mg/l) after 24 hours exposure are 0 %.
- Results with reference substance (positive control):
- EC0: 2 mg/L
EC100: > 5 mg/L
The sensitivity of the employed laboratoty population of Daphnia magna to the reference substance potassium dichromate has shown striking drift phenomena in recent years. The EC50 is no longer within the concentration range of 0.9 mg/L - 1.9 mg/L stated in the above-mentioned test guideline. - Validity criteria fulfilled:
- yes
- Conclusions:
- The EC0 was determined to be above 1000 mg/L (nominal conc.).
- Executive summary:
The test was performed according to the old test guideline of OECD 202 under GLP compliance. Both of the immobility values at the two test concentrations (707 mg/L and 1000 mg/L) after 24 hours exposure are 0 %. This result showed that the EC0 was determined to be above 1000 mg/L (nominal conc.).
Referenceopen allclose all
Description of key information
The short-term toxicity to aquatic invertebrates was tested in with an old OECD 202 test over 24h (EC50 > 1000 mg/L) [disregarded]. Additionaly a long-term toxicity study according to OECD 211 was conducted. Within this study the EC50(48h) was determined to be > 100 mg/L (highest tested concentration).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- > 100 mg/L
Additional information
The short-term toxicity to aquatic invertebrates is assessed with a long-term study with aquatic invertebrates. Within this long-term study the EC50(48h) was determined to be > 100 mg/L.
A dissregarded acute daphnia test is also available. It was performed according to the old test guideline of OECD 202 over 24h under GLP compliance. Both of the immobility values at the two test concentrations (707 mg/L and 1000 mg/L) after 24 hours exposure are 0 %. This result showed that the EC0 (24h) was determined to be above 1000 mg/L (nominal conc.).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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