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EC number: 954-543-1 | CAS number: 2489703-47-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 04-02-2021 to 26-03-2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Guideline study performed under GLP. All relevant validity criteria were met.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- <= -66.7 °C
- Atm. press.:
- ca. 1 atm
- Decomposition:
- no
- Sublimation:
- no
- Remarks on result:
- other: mean melting point (n = 2)
- Conclusions:
- The melting temperature of the test item has been determined to be -66.7 °C (or 206.45 K). At above this temperature the substance is considered to be liquid.
- Executive summary:
The melting temperature was determined using OECD TG 102 and EU Method A.1 with the Differential Scanning Calorimetry method under GLP. The guideline defines the melting temperature as: the temperature at which the phase transition from solid to liquid state occurs at atmospheric pressure and this temperature ideally corresponds to the freezing temperature. During DSC cooling an exothermic effect was observed which were due to crystallization of the test item between -90°C and -50°C. Subsequently upon heating an endothermic effect was seen indicating melting of the test item. The melting temperature was determined as the mean melting temperature of Experiment 1 (-66.873°C) and Experiment 2 (-66.602°C), respectively. It was concluded that the melting temperature of the test item is -66.7°C (or 206.45K). At above this temperature the substance is considered to be liquid.
Reference
(i) Preliminary study
Starting at 300°C, the weight of the sample decreased significantly. At 354°C, the sample weight had decreased by 25%. After the experiment it was observed that the test item was evaporated from the sample container.
(ii) Main study
- Experiment 1: During cooling, a glass transition between -60°C and -90°C was found. The effect was obtained due to crystallization of the test item. During heating a glass transition was observed between -90°C and -50°C followed by an endothermic effect starting at 200°C. The inflection temperature of the first effect was -66.873°C. The second endothermic effect was most likely obtained due to boiling of the test item. Since the boiling effect did not appear complete no onset temperature was calculated. After the experiment it was observed that the test item had evaporated from the sample container. The first endothermic effect (-66.873°C) was obtained due to melting of the test item.
- Experiment 2: Was conducted as a duplicate of experiment 1, to examine the glass transition and/or the extrapolated onset of the melting temperature peak. In order to investigate the endothermic effect, more test item (3.35 mg) was utilized (rather than 2.56 mg, experiment 1). Similar results as in experiment 1 were obtained. The first inflection temperature was -66.602°C. The first endothermic effect (-66.602°C) was obtained due to melting of the test item. Again, later in the run the second endothermic effect was most likely obtained due to boiling of the test item but did not look complete. After the experiment it was observed that the test item had evaporated from the sample container.
- Experiment 3: Was conducted to further examine the boiling temperature of the test item, no cooling cycle was completed. More test item (4.38 mg) was utilized. Similar results as in experiment 1 and 2 were obtained (an endothermic effect starting at ca. 200°C). The endothermic effect did not appear to be complete. After the experiment it was observed that the test item had evaporated from the sample container.
- Experiment 4: Was conducted to further examine the boiling temperature of the test item. More test item (3.28 mg) was utilized, comparable to experiment 2. A higher heating rate of +50°C/minute was utilized. An exothermic peak was observed between 150°C and 250°C and an endothermic effect starting at 250°C directly followed by an exothermic peak. Based on these results decomposition reactions were considered the reason for these observed effects. After the experiment it was observed that the test item had evaporated from the sample container and the lid was ripped open.
- Experiment 5: Was conducted to further examine the boiling temperature of the test item utilizing a closed DSC crucible and a heating rate of +20°C/minute (comparable to experiments 1, 2 and 3). The test item mass was 3.47 mg, comparable to experiment 1 and 2. The endothermic effect did not shift significantly to higher temperatures. It demonstrated that reaction and/or decomposition of the test item caused the endothermic effect. After the experiment it was observed that the test item had evaporated from the sample container and the lid was ripped open.
The melting temperature was determined as the mean melting temperature of Experiment 1 (-66.873°C) and Experiment 2 (-66.602°C). Mean (n=2) : -66.7°C.
The boiling temperature could not be determined. Reaction and/or decomposition of the test item was observed during DSC experiment between +150°C and +200°C (423K – 473K) and at +250°C (523K). Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started (i.e. ca. +150°C or 423.15). Under the conditions of this study, the test item has no determinable boiling temperature below its decomposition temperature (ca. +150°C or 423.15), at atmospheric pressure.
Description of key information
Mp: -66.7 °C (or 206.45 K) at 1 atmosphere, OECD TG 102 : DSC Method, 2021
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -66.7 °C
Additional information
Key study : OECD TG 102, 2021 : The melting temperature was determined using OECD TG 102 and EU Method A.1 with the Differential Scanning Calorimetry method under GLP. The guideline defines the melting temperature as: the temperature at which the phase transition from solid to liquid state occurs at atmospheric pressure and this temperature ideally corresponds to the freezing temperature. During DSC cooling an exothermic effect was observed which were due to crystallization of the test item between -90°C and -50°C. Subsequently upon heating an endothermic effect was seen indicating melting of the test item. The melting temperature was determined as the mean melting temperature of Experiment 1 (-66.873°C) and Experiment 2 (-66.602°C), respectively. It was concluded that the melting temperature of the test item is -66.7°C (or 206.45K). At above this temperature the substance is considered to be liquid.
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