Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No immobility was observed in the 6.25, 12.5, 25 and 50 mg/l test concentrations over the 48-hour exposure period. In the 100 mg/l test concentration, no immobility was observed after 24 hours of exposure, and 25 % immobility was observed after 48 hours of exposure.
Based on these results after 24 hours of exposure, the EC0 (NOEC) is ≥100 mg/l and the LOEC, EC50 and EC100 are >100 mg/l. After 48 hours of exposure, the EC0 (NOEC) is 50 mg/l, the LOEC is 100 mg/l, and the EC50 and EC100 are >100 mg/l.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- > 100 mg/L
Additional information
The substance was tested for its acute toxicity to Daphnia magna over a period of 48 hours in a static system. The study was performed according to the OECD Guideline No. 202 Part I and the EEC Directive 92/69 C.2. The test method used for the conduct of this study is accredited according to EN 45001.
This test examined five nominal test article concentrations in the range from 6.25 to 100 mg/l over a test period of 48 hours.The test concentrations were spaced by a geometric progression factor of 2.0. Per concentration twenty daphnids (ten per replicate) were exposed to the test article. The actual test concentrations were determined analytically for three different test concentrations at the beginning and at the end of the 48-hour exposure period. Measured test article concentrations ranged from 97.8 to 107.7 % of nominal at the beginning, and from 84.1 to 107.8 % of nominal at the end of the test period. Based on these analytical results, the biological data are expressed as nominal concentrations of the substance.
5 % immobilization was observed in the control over the 48-hour exposure period. This occurrence is not significant and is within the accepted threshold of 10 % given by the OECD and EEC test guidelines for the control.
No immobility was observed in the 6.25, 12.5, 25 and 50 mg/l test concentrations over the 48-hour exposure period. In the 100 mg/l test concentration, no immobility was observed after 24 hours of exposure, and 25 % immobility was observed after 48 hours of exposure.
Based on these results after 24 hours of exposure, the EC0 (NOEC) is ≥100 mg/l and the LOEC, EC50 and EC100 are >100 mg/l. After 48 hours of exposure, the EC0 (NOEC) is 50 mg/l, the LOEC is 100 mg/l, and the EC50 and EC100 are >100 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
