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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 022
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-fluoro-4-methyl-1,3,2-dioxaphospholane
- Cas Number:
- 16415-09-1
- Molecular formula:
- C3H6FO2P
- IUPAC Name:
- 2-fluoro-4-methyl-1,3,2-dioxaphospholane
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- The required test concentrations were prepared by adding appropriate amount of stock solutions and made up to required volume using OECD alga medium.
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
Study design
- Test type:
- not specified
- Water media type:
- not specified
- Limit test:
- yes
- Total exposure duration:
- 72 h
Test conditions
- Test temperature:
- Temperature of Surrogate(°C):
- Dose Range Finding Study 22.3 to 22.9
- Limit test 22.3 to 22.8 - Nominal and measured concentrations:
- Nominal concentration: 100.0 mg/L
- Details on test conditions:
- Light Intensity(Lux):
- Dose Range Finding Study 6001 to 6841
- Limit test 5831 to 6154 - Reference substance (positive control):
- yes
- Remarks:
- 3, 5 - Dichlorophenol 97%
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- EC10
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Duration:
- 72 h
- Dose descriptor:
- EC20
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Key result
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Results with reference substance (positive control):
- The percent growth rate inhibition as compared with the control is found to be 0.10, 0.28, 0.55, 0.47, 1.10 and 3.08 at the tested concentrations of 0.01, 0.1, 1.0, 10.0, 50.0 and 100.0 mg/L respectively.
The percent growth rate inhibition as compared with the control is found to be 4.66
at the tested concentration of 100.0 mg/L.
The percent inhibition in yield as compared with the control is found to be 0.49, 1.38, 2.76, 2.37, 5.43 and 14.41 at the tested concentrations of 0.01, 0.1, 1.0, 10.0, 50.0 and 100.0 mg/L respectively.
The percent inhibition in yield as compared with the control is found to be 21.54 at the tested concentration of 100.0 mg/L.
Applicant's summary and conclusion
- Conclusions:
- The toxicity of test item OA-1300 was tested on alga Raphidocelis subcapitata.
The 72 hours EC10, EC20, EC50 values, NOEC and LOEC based on the growth rate and yield was calculated in terms of nominal test item concentration are reported in the following table:
Growth Rate & Yield
Endpoint
(mg/L)
EC10 >100 EC20 >100 EC50 >100
Lower limit >100 Lower limit >100 Lower limit >100
Upper limit >100 Upper limit >100 Upper limit >100
NOEC <100
LOEC <100
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.