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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2021-10-29 to 2022-03-15
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- Version / remarks:
- 2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Version / remarks:
- 2004
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- Samples were taken at test start (0 h) and test end (120 h). The samples were stabilized with 5 mL acetonitrile containing 0.2% formic acid at sampling (dilution factor 2).
- Buffers:
- - pH: 4
- Type of buffer: sodium hydroxide with mono potassium citrate
- pH: 7
- Type of buffer: ammonium acetate buffer
- pH: 9
- Type of buffer: sodium hydroxide with potassium chloride and boric acid
with Purified water (sterilized) as co-solvent - Details on test conditions:
- The test solutions were prepared at test start via stock solution. 4.95 mL of the sterile buffer solution were given into the test container. The test container was carefully spiked with 0.05 mL of stock solution. Afterwards, the vials were sealed immediately and shaken for homogenization. After the vials were sealed, they were transferred into the thermostat. The time between test item application and transfer to thermostat / analysis did not exceed 30 min.
Incubation time: 120 h
Photolytic effects were avoided by using an opaque water bath.
Samples were taken at test start (0 h) and test end (120 h). The samples were stabilized with 5 mL acetonitrile containing 0.2% formic acid at sampling (dilution factor 2). All test item containing samples were analyzed immediately (if possible less than 30 min until start of analyses, but at least not more than 2.5% of the total study time) with the analytical method acc. To part 13. The method was validated acc. to SANTE/2020/12830, Rev.1 with the parameters specified in part 14. The method validation procedure was not part of this GLP study. The incubation temperature was checked automatically once per hour and at least once per day manually. - Duration:
- 120 h
- pH:
- 4
- Temp.:
- 50 °C
- Initial conc. measured:
- 21 mg/L
- Duration:
- 120 h
- pH:
- 7
- Temp.:
- 50 °C
- Initial conc. measured:
- 20.8 mg/L
- Duration:
- 120 h
- pH:
- 9
- Temp.:
- 50 °C
- Initial conc. measured:
- 20.8 mg/L
- Number of replicates:
- Duplicates per pH and sampling date, single injections
- Positive controls:
- no
- Negative controls:
- no
- Remarks:
- Buffer solutions (pH value 4, 7 and 9) and co-solvent
- Preliminary study:
- Preliminary hydrolysis test for the determination of the stability of the test item in buffered, aqueous solution (pH 4, 7, 9).
- Transformation products:
- not measured
- Remarks:
- The test item Dibuthyltetraalkylguanidinium chloride was found to be hydrolytically stable at all pH conditions.
- Key result
- Remarks on result:
- hydrolytically stable based on preliminary test
- Validity criteria fulfilled:
- yes
- Conclusions:
- The test item Dibuthyltetraalkylguanidinium chloride was found to be hydrolytically stable at all
pH conditions. - Executive summary:
The test item Dibuthyltetraalkylguanidinium chloride was found to be hydrolytically stable at all pH conditions.
Reference
Description of key information
According to to OECD Guideline No. 111 (2004) and Council Regulation (EC) No. 440/2008, Method C.7. The test item Dibuthyltetraalkylguanidinium chloride was found to be hydrolytically stable at all pH conditions.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.