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Diss Factsheets
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EC number: 424-970-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- 1992
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.1 (Acute Toxicity for Fish)
- Version / remarks:
- 1992
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Storage temperature: at room temperature
Protected from light: no - Analytical monitoring:
- yes
- Details on sampling:
- Samples of the only loading rate and the control were taken at t = 0h (newly prepared media) and t= 24h (spent media after 24h). Samples of exactly 100g were taken in 100mL brown glass bottles and transferred on the same day for analyses.
- Vehicle:
- no
- Details on test solutions:
- A quantity of 0.3g of SDBR was accurately weighed out and mixed with three litres of DSWL-E in a glass Erlenmeyer flask with a tap atthe bottom, followed by 20h mechanical stirring and 4h standing. Then the medium (Water Soluble Fraction, WSF) was tapped off (the first 200 mL was discarded). New exposure media were prepared at each replacement.
DSWL-E was used as a control medium, together with a stirred DSWL-E control (prepared as the test substance loading rate). - Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- TEST ORGANISM
- Source: commercial hatchery (M.B. Ruysbroek B.V., Noordvliet 159, Maassluis, The Netherlands)
- Length at study initiation: 1.7±0.1 cm
- Weight at study initiation: 0.0542±0.005 g - Test type:
- semi-static
- Water media type:
- freshwater
- Remarks:
- The medium was prepared with ground water.
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Remarks on exposure duration:
- The animals were counted and checked for mortality after 3, 24, 48, 72 and 96 hours. At the same time the condition (swimming behaviour, colour or any other visually observable morphological or behavioral criterion) of the survivors was compared to that o
- Hardness:
- 213 mg CaCO3/L
- Test temperature:
- 24.8-25.4ºC
- pH:
- 8.2-8.3
- Dissolved oxygen:
- Lowest measured oxygen concentration: 8.1 mg O2/L
- Nominal and measured concentrations:
- Overview of analytical results is given below in tabular format.
- Details on test conditions:
- TEST SYSTEM
The test was performed in 2 liter all-glass beakers, each containing 1.5 liter of exposure medium; the beakers were covered with a watch glass. The exposure media were slightly aerated and replaced daily. At the beginning and at the end of the test, as well as at each replacement time (in the spent media just before replacement and in the newly prepared media just after dosing), the pH and the oxygen concentration of the exposure media were measured.
- No. of organisms per vessel: 10
TEST CONCENTRATIONS
- Test concentration: 100 mg/L (loading rate)
As no adverse effects were expected within the aqueous solubility, only one loading rate of 100 mg/L was tested. - Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.02 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Analytics performed t=0h and t=24h
- Details on results:
- No mortality was observed throughout the study.
- Sublethal observations / clinical signs:
No adverse effects were observed throughout the study.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 96h No Observed Effect Loading rate (NOEL) for acute toxicity of SDBR to fish was found to be greater or equal to a loading rate of 100 mg/L (corresponding to 0.022 mg/L analysed) when tested as a WSF.
Reference
Description of key information
The 96h No Observed Effect Loading rate (NOEL) for acute toxicity of SDBR to fish was found to be greater or equal to a loading rate of 100 mg/L (corresponding to 0.022 mg/L analysed) when tested as a WSF.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- EC50
- Effect concentration:
- > mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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