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EC number: 947-879-5 | CAS number: 2475232-73-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- March 2006
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- gas saturation method
Test material
- Reference substance name:
- 4-[(2E)-3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-2-enoyl]-N-[(4R)-2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide
- EC Number:
- 947-879-5
- Cas Number:
- 2475232-73-4
- Molecular formula:
- C23H18Cl2F4N2O4
- IUPAC Name:
- 4-[(2E)-3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluorobut-2-enoyl]-N-[(4R)-2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide
- Test material form:
- solid
- Details on test material:
- Off-white
Constituent 1
Results and discussion
Vapour pressureopen allclose all
- Key result
- Test no.:
- #1
- Temp.:
- 25.1 °C
- Vapour pressure:
- < 0 Pa
- Key result
- Test no.:
- #2
- Temp.:
- 25.1 °C
- Vapour pressure:
- < 0 Pa
- Key result
- Test no.:
- #3
- Temp.:
- 25.1 °C
- Vapour pressure:
- < 0 Pa
Any other information on results incl. tables
No test substance was detected in any of the condensation tubes indicating that the vapour pressure must be very low. The upper limit for the vapour pressure was determined by using the lowest check calibration concentration of 0.4032 µg. No substance peak could be detected. The vapour pressure must be less than 6.6 x 10-6 Pa at 25 °C.
Applicant's summary and conclusion
- Conclusions:
- The substance has a vapour pressure of less than 6.6 x 10-6 Pa at 25 °C.
- Executive summary:
The vapour pressure of the substance was determined under GLP to OECD TG 104 using the gas saturation method. Saturator columns were prepared by filling them with glass beads that had been previously treated with the test substance dissolved in dichloromethane. Glass wool plugs were placed near the inlet and outlet of the columns, which were then conditioned and thermostated at the test temperature for a sufficient time to remove volatile impurities by passing through a supply of dry nitrogen. Subsequently, the gas flow was set by mass flow controllers and the gas passed was passed over the sample for an appropriate collection time. Two condensation tubes wee placed in a cooling trap at at temperature of 2.0 °C. The transported test substance was condensated at this temperature. Different flow rates were chosen at each test temperature, ranging from 18.32 to 35.72 mL/minute. After completion of the test, the condensation tubes were disconnected from the columns and the amount of transferred test item in each of the condensation tubes was determined by HPLC. The definite test was conducted at 25 °C. No test substance could be detected in any of the condensation tubes. The vapour pressure of the substance was determined to be less than 6.6 x 10-6 Pa at 25 °C under these conditions.
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