Registration Dossier
Registration Dossier
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EC number: 601-147-9 | CAS number: 111988-49-9
Toxicity to other aquatic organisms
Administrative data
Link to relevant study record(s)
Description of key information
Additional information
One study adressing the endpoint toxicity to other organisms is
available. In this GLP study, the acute toxicity of the test item to
Xenopus laevis was assessed in a 48-hour static test. The test design
did not follow a specific guideline but methodologies from USEPA, OPPTS
Guideline 850.1075, USEPA-FIFRA, 40 CFR, Part 158, Guideline No. 72 -1
and OECD Guideline 203 were considered. X laevis tadpoles were exposed
to five concentrations of the test substance in the range between 6.25
and 100 mg a.i./L. The mean measured recovery of solutions analyzed on
day 0 and day 2 was between 96 and 100 % of nominal. Throughout the
exposure, organisms were healthy and appeared normal in the control,
6.25 and 12.5 mg a.i./L test levels. However, there was a single
mortality in the control group. Toxicant related mortalities (26.7 %)
only occurred in the 100 mg a.i./L level. The LC50 (48) was determined
to be > 100 mg a.i./L (nominal).
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