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Diss Factsheets

Administrative data

Endpoint:
adsorption / desorption, other
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988
Report date:
1988

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: EPA Guideline number: 835.1230
GLP compliance:
yes (incl. QA statement)
Type of method:
batch equilibrium method
Media:
soil

Test material

1
Chemical structure
Reference substance name:
4-(4-chlorophenyl)-2-phenyl-2-[(1H-1,2,4-triazol-1-yl)methyl]butanenitrile
EC Number:
406-140-2
EC Name:
4-(4-chlorophenyl)-2-phenyl-2-[(1H-1,2,4-triazol-1-yl)methyl]butanenitrile
Cas Number:
114369-43-6
Molecular formula:
C19H17ClN4
IUPAC Name:
4-(4-chlorophenyl)-2-phenyl-2-[(1H-1,2,4-triazol-1-yl)methyl]butanenitrile

Study design

Test temperature:
25°C

Batch equilibrium or other method

Analytical monitoring:
yes
Details on sampling:
Concentration of test solutions:
High: 0.334 ppm
Medium High: 0.224 ppm
Medium: 0.107 ppm
Low: 0.039 ppm

Radioassay was used to determine the concentration of each solution. Combustion radioassay was used to determine the concentration remaining in the soil.
Matrix propertiesopen allclose all
Matrix no.:
#1
Matrix type:
clay
% Clay:
56
% Silt:
20.8
% Sand:
23.2
% Org. carbon:
0.4
pH:
5.3
CEC:
4.5 meq/100 g soil d.w.
Matrix no.:
#2
Matrix type:
loam
% Clay:
22
% Silt:
48.8
% Sand:
29.2
% Org. carbon:
2.4
pH:
7.2
CEC:
15.7 meq/100 g soil d.w.
Matrix no.:
#3
Matrix type:
sand
% Clay:
6
% Silt:
0.8
% Sand:
93.2
% Org. carbon:
0.5
pH:
7.3
CEC:
2.1 meq/100 g soil d.w.
Matrix no.:
#4
Matrix type:
sandy loam
% Clay:
13.2
% Silt:
18
% Sand:
68.8
% Org. carbon:
2.2
pH:
5.4
CEC:
8.7 meq/100 g soil d.w.
Matrix no.:
#5
Matrix type:
silty clay loam
% Clay:
29.2
% Silt:
62
% Sand:
8.8
% Org. carbon:
1.2
pH:
7
CEC:
6.6 meq/100 g soil d.w.
Details on matrix:
Cecil Clay, Keeton Loam, Lakeland Sand, Pasquotank Sandy Loam, Lawrenceville Silty Clay Loam
Details on test conditions:
The adsorption properties of 14C test substance were studied on five soils by mixing the soil and an aqueous 0.01 N CaC12 solution of test substance, at ambient temperature and four concentration levels (nominally 0.3, 0.2, 0.1 and 0.03 ppm). After allowing 24 hours for equilibration, the concentration of test substance in solution was measured. The soils tested were clay, loam, sand, sandy loam and silty clay loam. The ratios of soil to solution were approximately 1:5 for the clay and sand, 1:20 for the loam and sandy loam and 1:12 for the silty clay loam. Desorption was determined by rinsing each of the soils used for the adsorption with fresh 0.01 N CaC12, and after 72 hours, measuring the distribution of test substance in both media. Radioassay was used to determine the concentration of each solution. Combustion radioassay was used to determine the concentration remaining in the soil.
Duration of adsorption equilibrationopen allclose all
Sample No.:
#1
Duration:
24 h
Sample No.:
#2
Duration:
24 h
Sample No.:
#3
Duration:
24 h
Sample No.:
#4
Duration:
24 h
Sample No.:
#5
Duration:
24 h
Duration of desorption equilibrationopen allclose all
Sample no.:
#1
Duration:
72 h
Sample no.:
#2
Duration:
72 h
Sample no.:
#3
Duration:
72 h
Sample no.:
#4
Duration:
72 h
Sample no.:
#5
Duration:
72 h

Results and discussion

Adsorption coefficientopen allclose all
Key result
Sample No.:
#1
Type:
Kd
Value:
5.07
Matrix:
Cecil Clay
% Org. carbon:
0.23
Key result
Sample No.:
#2
Type:
Kd
Value:
75.206
Matrix:
Keeton Loam
% Org. carbon:
1.39
Key result
Sample No.:
#3
Type:
Kd
Value:
7.563
Matrix:
Lakeland Sand
% Org. carbon:
0.29
Key result
Sample No.:
#4
Type:
Kd
Value:
115.396
Matrix:
Pasquotank Sandy Loam
% Org. carbon:
1.28
Key result
Sample No.:
#5
Type:
Kd
Value:
20.079
Matrix:
Lawrenceville Silty Clay Loam
% Org. carbon:
0.7
Key result
Sample No.:
#1
Type:
Koc
Value:
2 185.3
Matrix:
Cecil Clay
% Org. carbon:
0.23
Key result
Sample No.:
#2
Type:
Koc
Value:
5 402.3
Matrix:
Keeton Loam
% Org. carbon:
1.39
Key result
Sample No.:
#3
Type:
Koc
Value:
2 607.8
Matrix:
Lakeland Sand
% Org. carbon:
0.29
Key result
Sample No.:
#4
Type:
Koc
Value:
9 042.8
Matrix:
Pasquotank Sandy Loam
% Org. carbon:
1.28
Key result
Sample No.:
#5
Type:
Koc
Value:
2 884.6
Matrix:
Lawrenceville Silty Clay Loam
% Org. carbon:
0.7

Results: Batch equilibrium or other method

Adsorption and desorption constants:
Kd (ads,des):
Clay: (5.07, 7.10)
Loam: (75.21, 147.6)
Sand: (7.56, 2.33)
Sandy Loam: (115.4, 132.2)
Silty Clay Loam: (20.08, 33.00)
For the loam and sandy loam, the adsorption of test substance appears to be irreversible.

Koc:
The adsorption constant, Koc, for 14C test substance was calculated as an average of the values found for each soil and found to be 4425.

Cecil Clay: 2185.3
Keeton Loam: 5402.3
Lakeland Sand: 2607.8
Pasquotank Sandy Loam: 9042.8
Lawrenceville Silty Clay Loam: 2884.6
Recovery of test material:
To ensure that radioactivity was not lost due to adhesion of test substance to the sides of the centrifuge tubes used in the course of this study. 10 mL of each test solution were placed in an empty Teflon tube and shaken for 24 hours. Duplicate 0.5 mL samples of each solution were
radioassayed. There was no significant'loss of radioactivity in any of the test solutions.
Mass balance (%) at end of adsorption phaseopen allclose all
Sample no.:
#1
% Adsorption:
59.52
Remarks on result:
other: Fortification: 3.34 µg
Sample no.:
#1
% Adsorption:
60.36
Remarks on result:
other: Fortification: 2.24 µg
Sample no.:
#1
% Adsorption:
64.17
Remarks on result:
other: Fortification: 1.07 µg
Sample no.:
#1
% Adsorption:
64.46
Remarks on result:
other: Fortification: 0.39 µg
Sample no.:
#2
% Adsorption:
79.59
Remarks on result:
other: Fortification: 12.69 µg
Sample no.:
#2
% Adsorption:
80.7
Remarks on result:
other: Fortification: 8.51 µg
Sample no.:
#2
% Adsorption:
80.9
Remarks on result:
other: Fortification: 3.96 µg
Sample no.:
#2
% Adsorption:
80.15
Remarks on result:
other: Fortification: 1.44 µg
Sample no.:
#3
% Adsorption:
52.97
Remarks on result:
other: Fortification: 3.34 µg
Sample no.:
#3
% Adsorption:
54.41
Remarks on result:
other: Fortification: 2.24 µg
Sample no.:
#3
% Adsorption:
42.49
Remarks on result:
other: Fortification: 1.07 µg
Sample no.:
#3
% Adsorption:
44
Remarks on result:
other: Fortification: 0.39 µg
Sample no.:
#4
% Adsorption:
85.13
Remarks on result:
other: Fortification: 12.69 µg
Sample no.:
#4
% Adsorption:
86.52
Remarks on result:
other: Fortification: 8.51 µg
Sample no.:
#4
% Adsorption:
88.1
Remarks on result:
other: Fortification: 3.96 µg
Sample no.:
#4
% Adsorption:
85.03
Remarks on result:
other: Fortification: 1.44 µg
Sample no.:
#5
% Adsorption:
71.14
Remarks on result:
other: Fortification: 8.35 µg
Sample no.:
#5
% Adsorption:
72
Remarks on result:
other: Fortification: 5.6 µg
Sample no.:
#5
% Adsorption:
75.72
Remarks on result:
other: Fortification: 2.68 µg
Sample no.:
#5
% Adsorption:
78.26
Remarks on result:
other: Fortification: 0.98 µg
Transformation products:
no
Details on results (Batch equilibrium method):
Both TLC and HPLC indicate that the test substance triazole was stable to test conditions. No other radioactive residues were detectable in either the autoradiogram or the HPLC chromatogram.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The findings of this study demonstrate that the test substance has only slight potential for mobility in soil and should not contaminate ground water though leaching. The mean Koc value was 4425.