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EC number: 619-020-1 | CAS number: 94361-06-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Phototransformation in water
Administrative data
Link to relevant study record(s)
- Endpoint:
- phototransformation in water
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- Apr 2002
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Study type:
- direct photolysis
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guidelines for the Testing of Chemicals, Phototransformation of Chemicals in Water
- Version / remarks:
- 2000
- Deviations:
- yes
- Remarks:
- See section on "Any other information on materials and methods incl. tables"
- Qualifier:
- according to guideline
- Guideline:
- other: OECD TG 101; LN-Visible Absorption Spectra
- Version / remarks:
- May 1981
- Deviations:
- yes
- Remarks:
- See section on "Any other information on materials and methods incl. tables"
- GLP compliance:
- yes (incl. QA statement)
- Radiolabelling:
- yes
- Analytical method:
- high-performance liquid chromatography
- Light source:
- not specified
- Light spectrum: wavelength in nm:
- >= 190 - <= 820
- Temp.:
- 25 °C
- Initial conc. measured:
- 22.02 mg/L
- Temp.:
- 25 °C
- Initial conc. measured:
- 44.04 mg/L
- Temp.:
- 25 °C
- Initial conc. measured:
- 1 384 mg/L
- Temp.:
- 25 °C
- Initial conc. measured:
- 3 608 mg/L
- Reference substance:
- no
- Dark controls:
- yes
- Remarks on result:
- not measured/tested
- Remarks on result:
- not measured/tested
- Transformation products:
- not measured
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In a study conducted according to OECD TG 101, an OECD draft guideline and following GLP, the molar absorption coefficients ε are < 10 L/mol/cm at wavelengths ≥ 290 nm. Therefore, the test substance is expected to be stable to photolysis under environmentally relevant conditions.
- Executive summary:
The photolysis of the 14C–Triazole labelled test substance in water was studied according to OECD TG 101, an OECD draft guideline and following GLP. The UV-Visible spectra of the test substance was obtained in buffered aqueous solutions of pH 7.02 (with up to 10 % methanol added as co-solvent) and in neat methanol at 25 °C. The initial concentrations of the test substance were 22.02, 44.04, 1384 and 3608 mg/L. From the spectra, the molar absorption coefficients were determined to estimate the photolysis of the test substance.
Spectra were measured from 190 - 820 nm at a scan speed of 240 nm/min. The molar absorption coefficients for the test substance in methanol at 290 nm were low. No significant absorbance was detected in the region 290 - 800 nm. Since the molar absorption coefficients were ≤ 10 L/mol/cm at wavelengths ≥ 290 nm, no further studies concerning the direct phototransformation in sunlight are required.
Based on the findings, it is concluded that the test substance is stable to photolysis under environmentally relevant conditions.
Reference
FINDINGS
The molar absorption coefficients were calculated from the UV-Visible spectra of the test substance in methanol and methanol/buffer using the Beer-Lambert law, εi = Ai/C·d
where εi = the molar absorption coefficient at wavelength i, Ai = the sample absorbance at wavelength i, C = the molar concentration of the test substance solution and d = the solution cell path length (1.000 cm). Due to the low solubility of the test substance in the buffer medium, data are also presented for the test substance in methanol. The molar absorption coefficients for the test substance in methanol at 290 nm are low. The spectra obtained for the test substance in the buffered solution (methanolic) showed no absorbance above the baseline in the region 290-800 nm.
Table 1. UV-Visible spectrum of the test substance (4.746E-03 mol/L) in methanol.
Molar concentration (M) | 4.746E-03 | |||
Wavelength/nm | 259.4 | 266.0 | 274.6 | 290.0 |
Absorbance | 0.974 | 1.119 | 0.734 | 0.016 |
Molar absorption coefficient (L mol cm) | 205 | 236 | 155 | 3.37 |
Table 2. UV-Visible spectrum of the test substance (1.236E-02 mol/L) in methanol.
Molar concentration (M) | 1.236E-02 | |||
Wavelength/nm | 259.4 | 266 | 274.6 | 290 |
Absorbance | 2.485 | 0.818 | 1.862 | 0.020 |
Molar absorption coefficient (L/mol/cm) | 201 | 228 | 151 | 1.62 |
Table 3. UV-Visible spectrum of the test substance in 5 % methanol/buffer.
Molar concentration (M) | 7.546E-05 | ||
Wavelength/nm | 242.5 | 265.6 | 290 |
Absorbance | 0.04 | 0.015 | 0.00 |
Molar absorption coefficient (L/mol/cm) | 53.0 | 199 | --- |
Table 4. UV-Visible spectrum of the test substance in 10 % methanol/buffer.
Molar concentration (M) | 1.509E-04 | ||
Wavelength/nm | 242.5 | 265.4 | 290.0 |
Absorbance | 0.018 | 0.041 | 0.005 |
Molar absorption coefficient (L/mol/cm) | 119 | 272 | ** |
**Below the detection limit of the instrument.
Description of key information
Stable to photolysis under environmentally relevant conditions, irradiation with continuous light by UV-Visible spectra (measured wavelength: 190-800 nm), 25 °C, OECD TG 101 and an OECD draft guideline, Oliver & Hurt 2002
Key value for chemical safety assessment
Additional information
Only one study is available for this endpoint. The 14C–Triazole labelled test substance was studied according to OECD TG 101 and OECD draft guideline and following GLP (Oliver & Hurt 2002, Reliability 2). The UV-Visible spectra (measured wavelength: 190-820 nm) of the test substance was obtained in buffered aqueous solutions of pH 7.02 (with up to 10 % methanol added as co-solvent) and in neat methanol at 25 °C. The initial concentrations of the test substance were 22.02, 44.04, 1384 and 3608 mg/L. From the spectra, the molar absorption coefficients were determined to estimate the photolysis of the test substance. The molar absorption coefficients are ≤ 10 L/mol/cm at wavelengths ≥ 290 nm. It is concluded that the test substance is stable to photolysis under environmentally relevant conditions.
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