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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
flash point of flammable liquids
Data waiving:
study technically not feasible
Justification for data waiving:
the study does not need to be conducted because the flash point is only relevant to liquids and low melting point solids
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 June - 23 October 2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Version / remarks:
1998
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
EC No. 440/2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
Batch No.: S119 0711
Storage: At room temperature (approx. 15-25°C), dry
Key result
Melting / freezing pt.:
228.8 °C
Atm. press.:
>= 1 002 - <= 1 006 hPa
Decomposition:
yes
Decomp. temp.:
ca. 230 °C

During the heating phase a first endothermic effect was observed in the temperature range of 220 – 270 °C, which could be assigned to the melting of the test item. A second endothermic effect was observed in the temperature range of 280 – 390 °C.






























No.



Sample weight / mg



Onset of Effect / °C



Range of effect / °C



Weight loss / mg



Atmospheric pressure / hPa



PN19899



7.78



228.63
289.79



220 – 270 (endo)
280 – 390 (endo)



4.47



1005.6



PN19902



7.65



228.87
287.03



220 – 270 (endo)
280 – 390 (endo)



4.26



1002.0



Optical verification using the capillary method:


To verify the results of the DSC measurement, three additional measurements in melting capillaries were performed in the temperature range of 180 °C to 290 °C at a heating rate of 10 K/min. The test item melted and turned brown starting at a temperature of approx. 220 °C. At a temperature of 240 °C the test item was completely molten and dark brown.


Due to this result, the first endothermic effect can be assigned to the melting of the test item accompanied by its decomposition. As the onset temperatures in both tests do not deviate by more than 0.5 K from their mean value of 228.75 °C, this temperature can be used as melting point. The test item has a melting point of 228.8 °C accompanied by its decomposition, which could be confirmed by the capillary method.

Conclusions:
The test item Glycyl glycine (CAS no. 556-50-3) has a melting point of 228.8°C at atmospheric pressure (1002 – 1006 hPa) accompanied by its decomposition as determined by Differential Scanning Calorimetry according to Regulation (EC) No 440/2008 Method A.1. and OECD Test Guideline 102 (1995).
Executive summary:

The test item Glycyl glycine (CAS no. 556-50-3) has a melting point of 228.8°C at atmospheric pressure (1002 – 1006 hPa) accompanied by its decomposition as determined by Differential Scanning Calorimetry according to Regulation (EC) No 440/2008 Method A.1. and OECD Test Guideline 102 (1995).

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion