Registration Dossier
Registration Dossier
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EC number: 220-942-8 | CAS number: 2944-06-1
Endpoint summary
Administrative data
Description of key information
NOAEL (oral, rat, 90 days) = 347 mg/kg bw/day
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- NOAEL
- 347 mg/kg bw/day
- Study duration:
- subchronic
- Species:
- rat
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The evaluation of the toxicity of the substance after a repeated exposure is done by use of data on the similar substances. Justification for Read Across is given in Section 13 of IUCLID.
The available information on the similar substances is presented in the attached document in the summary.
Justification for classification or non-classification
For the classification of the substance as STOT-RE the dose in which significant toxic effects are observed is taken into consideration. If this dose is in the range of the guidance values indicated in the CLP Regulation (EC) No. 1272/2008 Annex I: 3.9.2.9.6 and Annex I: 3.9.2.9.7 then the substance is classified in Category 1 or Category 2 respectively.
Based on the available repeated dose toxicity studies, the substance is not classified for STOT-RE according to the CLP Regulation (EC) No. 1272/2008.
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