Registration Dossier
Registration Dossier
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EC number: 806-756-5 | CAS number: 1262985-24-9
Guidance on Safe Use
Administrative data
First-aid measures
Eye contact - rinse immediately with tap water for 10 minutes - open eyelids
forcibly
- consult a physician if irritation persists
Skin contact - remove immediately contaminated clothes, wash affected skin
with water and soap - do not use any solvents
Inhalation - remove the casualty to fresh air and keep him/her calm
- in the event of symptoms get medical treatment
Note to physician - treat symptomatically- General advice:
Do not leave the victim unattended.
- Following inhalation:
Move to fresh air.
If unconscious, place in recovery position and seek medical advice.
If symptoms persist, call a physician.
- Following skin contact:
If on skin, rinse well with water.
- Following eye contact:
Flush eyes with water as a precaution.
Remove contact lenses.
Protect unharmed eye.
Keep eye wide open while rinsing.
If eye irritation persists, consult a specialist.
- Following ingestion:
Keep respiratory tract clear.
Do not give milk or alcoholic beverages.
Never give anything by mouth to an unconscious person.
If symptoms persist, call a physician.
- Most important symptoms and effects: None known.
Fire-fighting measures
Suitable extinguishing media - adapt extinguishing media to surrounding fire conditions
- water spray jet, dry powder, foam, carbon dioxide
Specific hazards - formation of toxic combustion gases (hydrogen chloride, hydrogen
fluoride, nitrogen oxides) possible
- substance is hazardous for water: contain fire-fighting wastewater
Protection of fire-fighters - precipitate gases/vapours/mists with water spray
Special method of fire-fighting - if possible precipitate fire gases with a water jet- Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
- Unsuitable extinguishing media:
High volume water jet
- Special hazards arising from the substance or mixture:
Specific hazards during firefighting :
Do not allow run-off from fire fighting to enter drains or water courses.
Hazardous combustion products:
In case of fire hazardous decomposition products may be produced such as:
Carbon monoxide
Nitrogen oxides (NOx)
Gaseous hydrogen chloride (HCl).
Hydrogen fluoride
- Advice for fire fighter:
Special protective equipment
for firefighters: Wear self-contained breathing apparatus for firefighting if necessary.
Further information: Collect contaminated fire extinguishing water separately. This must not be discharged into drains.
Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations.
Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal precautions:
Avoid dust formation.
Avoid breathing dust.
Environmental precautions:
Prevent product from entering drains.
Prevent further leakage or spillage if safe to do so.
If the product contaminates rivers and lakes or drains inform respective authorities.
Methods and material for containment and cleaning up
Methods for cleaning up : Keep in suitable, closed containers for disposal.
Handling and storage
Precautions for safe handling
Advice on safe handling:
Smoking, eating and drinking should be prohibited in the application area.
Dispose of rinse water in accordance with local and national regulations.
Advice on protection against fire and explosion:
Provide appropriate exhaust ventilation at places where dust is formed.
Hygiene measures: When using do not eat or drink. When using do not smoke.
Wash hands before breaks and at the end of workday.
Further information on storage stability:
No decomposition if stored and applied as directed.
Packaging material: Suitable material: Stainless steel, Polyethylene bag in metal drum
Conditions for safe storage, including any incompatibilities
Requirements for storage areas and containers: Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Electrical installations / working materials must comply with the technological safety standards.
Further information on storage conditions:
Storage class (TRGS 510): 13, Non Combustible Solids
Storage temperature : Protected from heat and light
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
- Chemical name:
- (1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-)
- Class or division:
- Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances
- Packing group:
- Packing group III: Substances presenting low danger
- Labels:
- 9
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 3077
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
- Chemical name:
- (1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-)
- Class or division:
- Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances
- Packing group:
- Packing group III: Substances presenting low danger
- EmS code:
- F-A
- S-F
- Labels:
- 9
- Marine pollutant
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
- Chemical name:
- (1-Propanesulfonamide, N-[3-[[5-bromo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-)
- Class or division:
- Class 9: Miscellaneous dangerous substances and articles, including environmentally hazardous substances
- Packing group:
- Packing group III: Substances presenting low danger
- Labels:
- 9
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
OEL 0,01 mg/m3
Engineering Measures - Handling
Technical measures - processing in closed systems, if possible superposed by inert gas
(e.g. nitrogen)
- low probability of ignition: ground plant, avoid effective ignition
sources
- avoid dust formation
Personal protective equipment
Respiratory protection - in case of open handling or accidental release:
particle mask or respirator with independent air supply
Hand protection - protective gloves (eg made of neoprene, nitrile or butyl rubber)The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. This recommendation is only valid for the product mentioned in the safety data sheet and provided
by us and for the application specified by us. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time. The suitability for a specific workplace should be discussed with the producers of the protective gloves
Eye protection - Eye wash bottle with pure water
Tightly fitting safety goggles
Skin and body protection : Choose body protection according to the amount and concentration of the dangerous substance at the work place.
Stability and reactivity
Conditions to avoid
- warming
- light
Note - suspicion of autocatalytic, very violent exothermal decomposition
with a very high decomposition rate1. Reactivity
No dangerous reaction known under conditions of normal use.
2. Chemical stability
Stable under normal conditions.
Exothermic reaction
3. Possibility of hazardous reactions
Hazardous reactions: Exothermic reaction
No decomposition if stored and applied as directed.
4. Conditions to avoid
Exposure to light.
Exposure to moisture
5. Incompatible materials
No data available
6. Hazardous decomposition products
No data available
Disposal considerations
Waste from residues
- observe local/national regulations regarding waste disposal
- incinerate in qualified installation with flue gas scrubbing
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
