Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 279-075-9 | CAS number: 79135-28-7
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: no guideline followed; however, the study meets generally accepted scientific principles and it is acceptable for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 974
- Report date:
- 1974
Materials and methods
- Principles of method if other than guideline:
- Test method not specified: acute oral toxicity study in male rats by gavage
- GLP compliance:
- no
- Limit test:
- yes
Test material
- Reference substance name:
- Acid Brown 303
- IUPAC Name:
- Acid Brown 303
Constituent 1
Test animals
- Species:
- rat
- Sex:
- male
Administration / exposure
- Vehicle:
- DMSO
- Details on oral exposure:
- 1.5 ml per 100 g body weight
- Doses:
- 5000 mg/kg
- Details on study design:
- gavage
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- other: not classified within the CLP Regulation (EC 1272/2008)
- Conclusions:
- LD50 > 5000 mg/kg bw.
- Executive summary:
Acute oral toxicity of test substance was assessed in male rats. Test animals were treated by gavage at 5000 mg/kg bw.
LD50 was determined to be > 5000 mg/kg bw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
