Registration Dossier
Registration Dossier
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EC number: 217-615-7 | CAS number: 1910-42-5
Endpoint summary
Administrative data
Description of key information
Reliable and valid studies are available on the acute and long-term toxicity of the substance to aquatic freshwater and marine species from three trophic levels (fish, invertebrates, algae). Furthermore, a reliable and valid study on the toxicity to microorganisms in activated sewage sludge is available.
Additional information
Table: Overview of key aquatic toxicity data available for the substance:
Study |
Species |
Guideline/ GLP |
Endpoint |
Effect value |
Reference |
Fish short-term toxicity (freshwater) |
Pimephales promelas |
OECD TG 203/ GLP |
96-h LC50 |
6.48 mg/L |
Claude 2014 |
Fish long-term toxicity (freshwater) |
Pimephales promelas |
OECD TG 210/ GLP |
33-d NOEC |
0.13 mg/L |
Claude 2014 |
Invertebrates short-term toxicity (freshwater) |
Daphnia magna |
OECD TG 202/ GLP |
48-h EC50 |
6.1 mg/L |
Allison 1990 |
Invertebrates long-term toxicity (freshwater) |
Daphnia magna |
OECD TG 211/ GLP |
21-d NOEC |
0.13 mg/L |
Claude 2014 |
Aquatic algal toxicity (freshwater) |
Navicula pelliculosa |
OECD TG 201/ GLP |
96-h ErC50 96-h NOErC |
0.47 µg/L 0.29 µg/L |
Smyth 1992 |
Microorganism toxicity |
Activated sludge |
OECD TG 209/ GLP |
3-h EC50 |
29.62 mg/L |
Hammesfahr 2018 |
Fish short-term toxicity (saltwater) |
Cyprinodon variegatus |
OECD TG 203/ GLP |
96-h LC50 |
>57 mg/L |
Claude 2014 |
Fish long-term toxicity (saltwater) |
Cyprinodon variegatus |
OECD TG 210/ GLP |
33-d NOEC |
2.55 mg/L |
Claude 2014 |
Invertebrates short-term toxicity (saltwater) |
Americamysis bahia |
OPPTS 850.1035/ GLP |
96-h LC50 |
0.31 mg/L |
Claude 2013 |
Invertebrates long-term toxicity (saltwater) |
Americamysis bahia |
OPPTS 850.1350/ GLP |
28-d NOEC |
0.0523 mg/L |
Claude 2014 |
Aquatic algal toxicity (saltwater) |
Skeletonema costatum |
FIFRA 123-2 |
96-h ErC50 96-h NOErC |
8.13 mg/L 0.21 mg/L |
Smyth 1992 |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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