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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Version / remarks:
13 April 2004
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

1
Chemical structure
Reference substance name:
Adipic acid, ammonium salt
EC Number:
242-809-3
EC Name:
Adipic acid, ammonium salt
Cas Number:
19090-60-9
Molecular formula:
C6H10O4.xH3N
IUPAC Name:
ammonium 5-carboxypentanoate
Test material form:
solid: crystalline

Study design

Analytical method:
liquid chromatography

Results and discussion

Partition coefficientopen allclose all
Key result
Type:
log Pow
Partition coefficient:
< 0.3
Temp.:
25 °C
pH:
ca. 2.7
Key result
Type:
log Pow
Partition coefficient:
< 0.3
Temp.:
25 °C
pH:
ca. 8.8

Applicant's summary and conclusion

Conclusions:
In the course of this study the partition coefficient (Pow) of Ammonium Adipate was
determined using high performance liquid chromatography.
Retention times measured for Ammonium Adipate (1.64 min (Method 1), 2.34 min (Method
2) and 1.50 min (Method 3)) are lower than the retention time of the first eluting standard;
2-Butanone (3.76 min (Method 1), 3.74 (Method 2) and 3.82 min (Method 3)). This result
shows that log Pow of Ammonium Adipate is lower than the calibrated range.
Using the HPLC method the log Pow of Ammonium Adipate was determined to be < 0.3.
Executive summary:

In the course of this study the partition coefficient (Pow) of Ammonium Adipate was
determined using high performance liquid chromatography.
Retention times measured for Ammonium Adipate (1.64 min (Method 1), 2.34 min (Method
2) and 1.50 min (Method 3)) are lower than the retention time of the first eluting standard;
2-Butanone (3.76 min (Method 1), 3.74 (Method 2) and 3.82 min (Method 3)). This result
shows that log Powof Ammonium Adipate is lower than the calibrated range.
Using the HPLC method the log Powof Ammonium Adipate was determined to be < 0.3.