Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 256-233-5 | CAS number: 45320-65-8
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-10-05 to 2017-10-05
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to other study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 107 (Partition Coefficient (n-octanol / water), determination from individual solubilities in water and 1-octanol.
- Version / remarks:
- See also "Guidance on Information Requirements and Chemical Safety Assessment Chapter R.7a:
Endpoint specific guidance" , Version 5 , December 2016, page 65ff. - Principles of method if other than guideline:
- The partition coefficient is usually determined by shake-flask method (log Pow = -2 to 4, OECD Guideline 107) or HPLC method (log Pow = 0 to 6, OECD Guideline 117).
Earlier investigations showed, that neither method is suitable to determine the partition coefficient of this substance. - GLP compliance:
- no
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
- Key result
- Type:
- log Pow
- Partition coefficient:
- 8
- Temp.:
- 20 °C
- Remarks on result:
- other: The partition coefficient of the test item was calculated from the individual solubilities in 1-octanol and water at 20°C, respectively.
- Details on results:
- The water solubility of the test item was determined under reference 16-18653-3 j 17-00907-3:
< 2.5 μg/I (For the calculation, a value of 2.5 μg/l is used)
The 1-Octanol solubility of the test item was determined under reference 16-18653-4 j 17-00907-4:
250 g/I (estimated from the preliminary test described in OECD 105) - Conclusions:
- The partition coefficient of N,N'-[(methylimino)bis(trimethylene)] bis(oleamide) was calculated from the individual solubilities in 1 -octanol and water at 20°C, respectively.
Water solubility: < 2.5 μg/L
Solubility in 1-Octanol: is 250 g/L
The log Pow was calculated as: log (Pow) 8.0.
Reference
The Log Pow is calculated from the individual solubilities in water and 1 -Octanol, based on the following equitation:
Pow = solubility of test item in 1 -octanol / solubility of test item in water
Pow = 250 g/L / 2.5 μg/L
Pow = 1E08
log Pow = 8.0
Description of key information
The partition coefficient of N,N'-[(methylimino)bis(trimethylene)] bis(oleamide) was calculated from the individual solubilities in 1 -octanol and water at 20°C, respectively.
Water solubility: < 2.5 μg/L
Solubility in 1-Octanol: is 250 g/L
The log Pow was calculated as: log (Pow) 8.0.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 8
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
