Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 918-919-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Stability in organic solvents and identity of relevant degradation products
Administrative data
Link to relevant study record(s)
- Endpoint:
- stability in organic solvents and identity of relevant degradation products
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015-10-15
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- other: SOP 00191
- Version / remarks:
- Version 2
- Deviations:
- no
- Principles of method if other than guideline:
- - The content of the active substances was not considered for preparation of formulations.
- For 1 mg/mL: Approx. 200 mg of the test item were dissolved and homogenized in 20 mL with acetone / olive oil (4+1) by manual shaking.
- For 500 mg/mL: Approx. 10000 mg of the test item were dissolved and homogenized in 20 mL with acetone / olive oil (4+1) by manual shaking.
Analysis via HPLC-UV - GLP compliance:
- yes
- Specific details on test material used for the study:
- Expiry date: 2016-07-01
- Test substance stable:
- yes
- Remarks:
- Test item is stable for at least 4 days in the refrigerator in acetone / olive oil (4+1).
- Transformation products:
- no
- Conclusions:
- Test item phosphorothioyltris(oxybenzene-4,1-diylcarbamoyloxyethane- 2,1-diyl) trisprop-2-enoate is stable in acetone / olive oil (4+1) for at least 4 days in the refrigerator.
- Executive summary:
According to SOP 00191 Version 2, the 1 mg/mL and 500 mg/mL formulations of the test item, phosphorothioyltris(oxybenzene-4,1-diylcarbamoyloxyethane-2,1-diyl) trisprop-2-enoate, in acetone / olive oil (4 +1) are homogenous and stable for at least 4 days in the refrigerator.
- Endpoint:
- stability in organic solvents and identity of relevant degradation products
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015-10-16
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- other: SOP 00191
- Version / remarks:
- Version 2
- Deviations:
- no
- Principles of method if other than guideline:
- For 5 mg/mL: Approx. 240 mg of the test item were dissolved and homogenized in 20 mL with PEG 400 by manual shaking.
For 200 mg/mL: Approx. 4800 mg of the test item were dissolved and homogenized in 10 mL with PEG 400 by manual shaking.
Analysis via HPLC-UV - GLP compliance:
- yes
- Specific details on test material used for the study:
- Expiry date: 2016-07-01
- Test substance stable:
- yes
- Remarks:
- Test item is stable for at least 2 days at room temperature in PEG 400.
- Transformation products:
- no
- Conclusions:
- Test item phosphorothioyltris(oxybenzene-4,1-diylcarbamoyloxyethane- 2,1-diyl) trisprop-2-enoate is stable in PEG 400 for at least 2 days at room temperature.
- Executive summary:
According to SOP 00191 Version 2, the 5 mg/mL and 200 mg/mL formulations of the test item, phosphorothioyltris(oxybenzene-4,1-diylcarbamoyloxyethane-2,1-diyl) trisprop-2-enoate, in PEG 400 are homogenous and stable for at least 2 days at room temperature.
Referenceopen allclose all
The stability of the test item was determined based on the monitoring of the main peak present in the HPLC-UV chromatogram of the test item.
Nominal value | Theoretical value | Content Test Item [mg/mL]* | Recovery as % of theoretical value | ||||
[mg/mL] | [mg/mL] | Start | After 2 hours | After 4 days | Start | After 2 hours | After 4 days |
1 | 9.65 | 9.67 | 9.74 | 9.74 | 100 | 101 | 101 |
500 | 500.94 | 517.64 | 512.01 | 517.21 | 103 | 102 | 103 |
* mean values of two replicates
The stability of the test item was determined based on the monitoring of the main peak present in the HPLC-UV chromatogram of the test item.
Nominal value | Theoretical value | Content Test Item [mg/mL] | Recovery as % of theoretical value | ||
[mg/mL]* | [mg/mL]* | Start | After 2 days | Start | After 2 days |
5 | 4.967 | 5.162 | 4.418 | 104 | 89 |
200 | 202.750 | 214.165 | 205.315 | 106 | 101 |
* mean values of two replicates
Description of key information
Test item phosphorothioyltris(oxybenzene-4,1-diylcarbamoyloxyethane-2,1-diyl) trisprop-2-enoate is stable in PEG 400 for at least 2 days at room temperature and in acetone / olive oil (4:1) for at least 4 days in the refrigerator.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.