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EC number: 204-385-8 | CAS number: 120-32-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
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- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
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- Endpoint summary
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- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
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- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
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Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
Koc: 2511 (OECD 121, Jungheim, 2006)
log Koc: 3.43 (OECD 121, Jungheim, 2006)
Key value for chemical safety assessment
- Koc at 20 °C:
- 2 511
Additional information
The adsorption coefficient Koc of Chlorophene (CAS 120-32-1) was estimated on soil via a screening test (A) and a test design with four different soil types (B).
A) Screening test
The adsorption coefficient Koc of chlorophene on soil was estimated using HPLC (Jungheim, R., 2006). The test was performed according to OECD guideline 121 (Proposal for New Guideline, 2001). Six reference standards of known Koc were analysed on a HPLC system to determine an average capacity factor k’. Sodium nitrate was used to determine the HPLC system dead time (t0). A regression curve was plotted, with determined k’ values and the known Koc values (log k’ versus log Koc). Chlorophene was analysed on the same HPLC system during the same sample sequence as the reference substances. The Koc value for chlorophene was estimated by interpolation from the reference substance regression line. The estimated Koc value for chlorophene is log 3.43 (Koc = 2511), (Jungheim, 2006) and summarised in Table 1.
Table 1: HPLC retention time data and Koc calculations for chlorophene and reference substances obtained in an OECD screening test (Jungheim, 2006)
Calibration substance |
Retention time [tr] = min* |
Capacity factor k’* |
Log k’* |
Log Koc |
2-Nitrobenzamide |
5.535 |
0.678 |
- 0.169 |
1.45 |
3-Nitrobenzamide |
5.680 |
0.722 |
- 0.141 |
1.95 |
3,5-Dinitrobenzamide |
6.018 |
0.824 |
- 0.084 |
2.31 |
Triazoxide |
7.389 |
1.240 |
0.093 |
2.44 |
Naphthalene |
8.276 |
1.509 |
0.179 |
2.75 |
Phenanthrene |
9.550 |
1.896 |
0.278 |
4.09 |
Chlorophene (Test item) |
8.532 |
1.587 |
0.201 |
3.43 |
* mean value from 3 single values
B) Adsorption and desorption in at least three soil types
Aqueous solutions of Chlorophene were equilibrated with four soil types and the adsorption and desorption coefficients and constants were determined (Meinerling, M., 2007). The concentration of the test item was determined using HPLC method. The experiment was conducted according to OECD Guidelines for Testing of Chemicals, Guideline No. 106 and Commission Directive 2001/59/EC, Method C.18. No relevant deviations from the guidelines occurred.
In the screening test the adsorption kinetics were estimated at one concentration of the test item using four soil types. The percentage of adsorption was calculated after different time intervals. The equilibrium was reached after 24 h incubation time. The percent adsorbed was within 20% to 80% range.The calculated distribution coefficient was in the range of 16 to 98 mL/g. The corresponding adsorption coefficient was in the range from 1361 to 2974 mL/g. Desorption was estimated at one concentration of the test item using 4 different soil types. The desorption of the adsorbed test item after 24 h from the different soil types ranged from 18% up to 39% desorption. The Freundlich adsorption coefficients (KF ads values) varied between 7.8 and 41.6 mL/g. Related to organic carbon, adsorption coefficients between 650 and 1484 mL/g have been calculated. Freundlich coefficients determined for the desorption (KF des values) were lower as those determind for the adsorption (range of KFdes: 0.0-0.6 mL/g). Results are summarized within Table 2.
Table 2: Summary of Results
Soil description |
% org C |
Time to reach Ads.Equilibrium [h] |
Adsorption(1) [%] |
Distribution1 Coefficient Kd [mL/g] |
Adsorption1 Coefficient Koc [mL/g] |
Freundlich Intercept |
Adsorption Isotherm Slope |
Freundlich Ads. Coeff KFads [mL/g] |
Freundlich Ads.Coeff KFoc [mL/g] |
Lufa 2.1 -sand |
1.2 |
24 |
38.4 |
15.7 |
1360.9 |
0.89 |
1.163 |
8 |
650 |
Lufa 2.2 – loamy sand |
2.4 |
24 |
64.4 |
52.9 |
2239.4 |
1.48 |
1.148 |
30 |
1263 |
Lufa 6S –clayey loam |
1.8 |
24 |
60.9 |
40.4 |
2205.0 |
1.43 |
1.097 |
27 |
1484 |
Eurosoil3 –loam |
3.3 |
24 |
79.2 |
98.2 |
2974.2 |
1.62 |
1.261 |
42 |
1260 |
Mean value calculated from exact raw data
(1): calculated from adsorption kinetic experiment
[LogKoc: 3.4]
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