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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB
Justification:

This substance/mixture contains no components considered
to be either persistent, bioaccumulative and toxic (PBT), or
very persistent and very bioaccumulative (vPvB) at levels of 0.1 % or higher


Justification:


Persistence and degradability
Product:
Biodegradability : Test Type: aerobic
Biodegradation: 79 %
Exposure time: 28 d
Method: ISO 10708
GLP: yes
Components:
Reaction products of DL-methionine and C18 unsaturated fatty acid chloride and
isopropanol:
Biodegradability : Test Type: aerobic
Inoculum: Other
Result: Readily biodegradable.
Biodegradation: 79 %
Related to: Biochemical oxygen demand
Exposure time: 28 d
Method: Other
GLP: yes


 


Bioaccumulative potential:


Product:
Bioaccumulation : Remarks: no data available
Components:
Reaction products of DL-methionine and C18 unsaturated fatty acid chloride and
isopropanol:
Partition coefficient: noctanol/water
: log Pow: 3,1 (20 °C)
pH: 5 - 7
Method: Other
GLP: no
Remarks: Calculated on the basis of measured solubilities in
water at pH 7 and in n-octanol.


Toxicity
Product:
Toxicity to fish : LC50 (Cyprinodon variegatus (sheepshead minnow)): > 100
mg/l
Exposure time: 96 h
Method: PARCOM Protocol Part B
GLP: yes
Toxicity to daphnia and other
aquatic invertebrates
: LC50 (Acartia tonsa): 354 mg/l
Exposure time: 48 h
Method: ISO 14669 and PARCOM method
GLP: yes
LC50 (Corophium volutator (sandhopper)): 7461 mg/kg
Exposure time: 10 d
Method: PARCOM 1995 Part A
GLP: yes
Toxicity to algae/aquatic
plants
: EC50 (Skeletonema costatum (marine diatom)): 412 mg/l
Exposure time: 72 h


Method: ISO 10253
GLP: yes
Toxicity to microorganisms :
Remarks: no data available
Components:
Reaction products of DL-methionine and C18 unsaturated fatty acid chloride and
isopropanol:
Toxicity to fish : LC50 (Cyprinodon variegatus (sheepshead minnow)): > 100
mg/l
End point: mortality
Exposure time: 96 h
Test Type: static test
Analytical monitoring: yes
Method: OECD Test Guideline 203
GLP: yes
Toxicity to daphnia and other
aquatic invertebrates
: LC50 (Acartia tonsa): 354 mg/l
End point: mortality
Exposure time: 48 h
Test Type: static test
Analytical monitoring: yes
Method: ISO 14669 and PARCOM method
GLP: yes
Toxicity to algae/aquatic
plants
: ErC50 (Skeletonema costatum (marine diatom)): 412 mg/l
End point: Growth rate
Exposure time: 72 h
Test Type: static test
Analytical monitoring: yes
Method: ISO 10253
GLP: yes
NOEC (Skeletonema costatum (marine diatom)): 321 mg/l
End point: Growth rate
Exposure time: 72 h
Test Type: static test
Analytical monitoring: yes
Method: ISO 10253
GLP: yes
Toxicity to fish (Chronic
toxicity)
: Remarks: no data available
Toxicity to daphnia and other
aquatic invertebrates
(Chronic toxicity)
: Remarks: no data available
Sediment toxicity : LC50: 7461 mg/l
Analytical monitoring: yes
Sediment: Natural sediment
Exposure duration: 10 h
Basis for effect: mortality


Method: Other
GLP: yes