Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 619-490-8 | CAS number: 303186-36-9
Endpoint summary
Administrative data
Description of key information
With the test material XXXX one oral and one dermal acute toxicity study were conducted. Both studies showed no mortality, no body weight change and no signs of toxicity. No acute toxicity studies for inhalative administration are available.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
Additional information
Oral route of administration
XXXXXXX was tested for acute toxicity in rats after oral administration of 2000 mg/kg body weight. This study was performed according to the ,,Acute toxic class method" (ATC).
No signs of toxicity were detected in the 3 male and 3 female rats after treatment and no rat died. The gross pathological examination revealed no organ alterations.
Dermal route of administration
XXXXXX was tested for acute toxicity in 5 male and 5 female rats after dermal administration of 2000 mg/kg body weight.
No signs of toxicity were detected in the rats (5 males and 5 females) after treatment with 2000 mg/kg. There were no deaths during the course of the study. The body weight development was inconspicuous.The gross pathological examination revealed no organ alterations.
Based on the result of this study, XXXXXX can be considered to have no acute toxic potential and to have a LD50 value higher than 2000 mg/kg after dermal application to rats.
Summary
Based on the result of this study, XXXXXX can be considered to have no acute toxic potential and to have a LD50 value higher than 2000 mg/kg after dermal application to rats.
Justification for classification or non-classification
Based on the results for acute oral and dermal toxicity in rats, XXXXXXX is considered to have no acute toxic potential. The expected LC50 values are higher than 2000 mg/kg bw after oral and after dermal administration to rats.Therefore, XXXXXXX is not classified according to EU Directive 67/548/EC amended and repealed by EU Regulation No.1272/2008 and CLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
