Registration Dossier
Registration Dossier
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EC number: 209-269-0 | CAS number: 564-20-5
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1965
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 965
- Report date:
- 1965
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Guideline:
- other: The study was performed in 1965, before any Guideline.
- GLP compliance:
- no
- Remarks:
- The study wa performed in 1965, before GLP had been implemented.
- Limit test:
- yes
Test material
- Reference substance name:
- [3aR-(3aα,5aβ,9aα,9bβ)]decahydro-3a,6,6,9a-tetramethylnaphth[2,1-b]furan-2(1H)-one
- EC Number:
- 209-269-0
- EC Name:
- [3aR-(3aα,5aβ,9aα,9bβ)]decahydro-3a,6,6,9a-tetramethylnaphth[2,1-b]furan-2(1H)-one
- Cas Number:
- 564-20-5
- Molecular formula:
- C16H26O2
- IUPAC Name:
- [3aR-(3aα,5aβ,9aα,9bβ)]decahydro-3a,6,6,9a-tetramethylnaphth[2,1-b]furan-2(1H)-one
- Test material form:
- solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: CF Nelson
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- not specified
- Doses:
- 3250 mg/kg b.w.
- No. of animals per sex per dose:
- Not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 3 250 mg/kg bw
- Mortality:
- Death was observed at 3250 mg/kg b.w., however it was attributed to physical properties (insolubility) of the substance and not its pharmacological properties.
Applicant's summary and conclusion
- Conclusions:
- In rats LD50 was determined to be 3250 mg/kg b.w.
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