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EC number: 606-204-1 | CAS number: 19022-77-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
According to the assessment of the four hydrolysation products, aluminum;3 -oxobutanoate is acutely not harmful to aquatic organismns.
Additional information
In the presents of water, the substance aluminum;3-oxobutanoate (CAS 15598-24-0) will hydrolyze spontaneously and irreversible to the four components as listed below. Accordingly, the hazard assessment is based on information on these four hydrolyzation products. Since non of the hydrolyzation products are harmful or toxic to the environment, aluminum;3-oxobutanoate does not need to be classified as well.
CAS# Name % after hydrolyzation Assessment based on
541-50-4 Acetoacetic acid
44.5 Expert judgement
78-92-2 2-Butanol
31.7 ECHA disseminated dossier
67-56-1 Methanol
12.4 ECHA disseminated dossier
21645-51-2 Aluminum hydroxide 11.3
ECHA disseminated dossier
Acetoacetic acid CAS 541-50-4
Acetoacetic acid acts as an intermediate in the mamal metabolism as well as in microorganisms. It is produced in mitochondria of the liver from acetoacetyl Coenzyme A (CoA). It is then released into the bloodstream as an energy source during periods of fasting, exercise, or as a result of type 1 diabetes mellitus. Thus, toxic effects at realistic environmental concentrations can be neglected. Furthermore, as it can be easily metabolized by all animals and is an natural occurring carbon acid, a high level of (bio)degradation in the aquatic compartment is expected. Thus, acetoacetic acid does not contribute to a potential aquatic effect of aluminum;3-oxobutanoate.
2-Butanol CAS 78-92-2
Based on the read-across substance, methyl ethyl ketone (CAS No. 78-93-3), the substance is predicted to possess a 96-hour LC50 in freshwater fish of 2993 mg/L,a 48-hour EC50 in daphnia magna of 308 mg/L and a 96-hour EC50 in aquatic algae and cyanobacteria of 2029 mg/L (ECHA disseminated dossier). The toxicity threshold, which is approximately equivalent to the LC3, for microorganism was determined to be 500 mg/L. This substance is not considered to be acutely toxic to fish, or aquatic invertebrates, nor is it considered to be toxic to aquatic algae, cyanobacteria, or microorganisms. Moreover, 2-Butanol is considered to be readily biodegradable. Thus, 2-Butanol does not contribute to a potential aquatic effect of aluminum;3-oxobutanoate.
Methanol CAS 67-56-1
Methanol is the first and simplest member of the series of aliphatic alcohols. Like other non-reactive, non-ionizable organic chemicals ("neutral organics") such as ketones, ethers, alkyl halides, aryl halides and aromatic hydrocarbons methanol is expected to exert toxicity to aquatic species through simple narcosis. A large amount of data on the toxicity of methanol is available for a broad spectrum of aquatic organisms (fish, invertebrates and algae). The results from the most reliable and relevant available studies are all well above 100 mg/L (see ECHA dossier).
Methanol is readily degradable under both aerobic and anaerobic conditions in a wide variety of environmental media including fresh and salt water, sediments and soils, ground water, aquifer material and industrial wastewater. Methanol does not significantly bioaccumulate in fish. Experimental BCFs of < 10 in fish species, including Cyprinus carpio and Leuciscus idus, have been reported (Hansch and Leo 1979, Gluth et al. 1985, Freitag et al. 1985, Howard 1990). Thus, methanol does not contribute to a potential aquatic effect of aluminum;3-oxobutanoate.
Aluminum hydroxide CAS 21645-51-2
There is a huge amount of ecotoxicity data available for aluminum hydroxide based on aluminum and it´s salts. A comprehensive data evaluation and hazard assessment is provided in the ECHA disseminated dossier. According to this assessment, aluminum hydroxide is not classified for the environment. Thus, aluminum hydroxide does not contribute to a potential aquatic effect of aluminum;3-oxobutanoate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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