Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 229-962-1 | CAS number: 6864-37-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Does not significantly accumulate in organisms
Key value for chemical safety assessment
Additional information
Concerning the bioaccumulation potential of 4,4'-methylenebis(2-methylcyclohexanamine) (CAS 6864-37-5, DMDC) a valid study was performed by NITE Japan (2002) according to OECD 305C (replaced); OECD 305-I (2012), with Cyprinus carpio as test species and using a flow-through procedure. This study was selected as key study. After 60 days, a max. BCF of < 60 was measured, indicating that the substance will not significantly bioaccumulate in organisms.
The experimental result is supported by calculated data (BASF SE, 2015, 2019). The BCF was calculated to be 15.29 L/kg; the substance is within the applicability domain of the estimation model (BCFBAF v3.01, submodel according to Meylan et al. 1997/1999; EPISuite v4.11). In addition, the BCF was calculated with the BCF baseline model v03.10 (Catalogic v5.13.1) to be 61.1 L/kg (log BCF = 1.79) without considering any mitigating factors. Metabolism, molecular size and water solubility had a mitigating effect on the bioaccumulation potential. The BCF was estimated to be 17.4 L/kg (log BCF = 1.24; BASF SE, 2019) if mitigating effects were considered. The substance was 100% within the applicability domain of the model.
Metabolites:
Metabolites (n = 128) from the degradation of 4,4'-methylenebis(2 -methylcyclohexanamine (CAS 6864 -37 -5) were predicted using the QSAR model Catalogic 301C v11.15. The metabolites are identified by the Smiles code. The table below also lists the estimated quantity of appearance from the degradationas well as the log Kow and the biodegradability (BOD prediction). The metabolites with a quantity of > 0.001 mol/mol parent are regarded to be relevant for the environmental assessment. It was attempted to identify the relevant metabolites either via the QSAR Toolbox and/or the advanced search option for substances on the ECHA website. In case a name and/or CAS number was assigned, the PBT/vPvB status acording to the ECHA website was checked.
Based on the available informatio nit can be concluded that only three metabolites (metab. no. 2, 117, 123) have a log Kow > 3. In addition these substances are not readily biodegradable. However, as their predicted quantitiy is below 0.001 mol/mol parent, they are not relevant for the PBT assessment of the parent substance's metabolites.
37 of the 128 metabolites have a predicted quantity of > 0.001 mol/mol parent and are regarded as relevant for further assessment. 26 of these metabolites are not readily biodegradable, but all of these 37 metabolites have a log Kow < 3; therefore, a significant bioaccumulation potential is not expected. It can be concluded that these substances are not PBT/vPvB substances.
Their toxicity (T) was not further assessed as no critical combination of potential P/vP (= not readily biodegradable) and potential B/vB (log Kow > 3) properties was observed.
Table: QSAR prediction for CAS-#6864 -37 -5 using CATALOGIC 301C v11.15 – July 2018 (OASIS CATALOGIC v5.13.1.156; metabolites with a quantity > 0.001 mol/mol parent after 28 d are highlighted by grey background and bold type; metabolite no: according to (Q)SAR model Catalogic v11.15 – July 2018 (OASIS CATALOGIC v5.13.156))
# |
Metab. |
Smiles |
Name |
Quantity |
Log Kow |
BOD pred. (% after 28 d) |
PBT-Assessment: |
Parent |
1 |
CC1CC(CC2CCC(N)C(C)C2)CCC1N |
4,4'-Methylenebis(2-methylcyclohexanamine) (CAS 6864-37-5) |
1.24E-01 |
2.30 |
39 |
not PBT/vPvB |
1 |
2 |
CC1CC(CC2CCC(=O)C(C)C2)CCC1N |
not identified |
7.95E-06 |
3.60 |
56 |
not checked |
2 |
3 |
CC1CC(CC2(O)CCC(=O)C(C)C2)CCC1N |
not identified |
7.95E-06 |
2.09 |
55 |
not checked |
3 |
4 |
CC1CC(CC2(O)CCC(=O)OC(C)C2)CCC1N |
not identified |
8.82E-02 |
1.64 |
54 |
not identified |
4 |
5 |
CC1CC(CC(O)(CCC(O)=O)CC(C)O)CCC1N |
not identified |
7.07E-06 |
-1.24 |
58 |
not checked |
5 |
6 |
CC1CC(CC(O)(CC(C)O)C=CC(O)=O)CCC1N |
not identified |
7.07E-06 |
0.04 |
58 |
not checked |
6 |
7 |
CC1CC(CC(O)(CC(C)O)C(O)CC(O)=O)CCC1N |
not identified |
7.07E-06 |
-2.78 |
57 |
not checked |
7 |
8 |
CC1CC(CC(O)(CC(C)O)C(=O)CC(O)=O)CCC1N |
not identified |
7.07E-06 |
-2.37 |
57 |
not checked |
8 |
9 |
CC1CC(CC(O)(CC(C)O)C(O)=O)CCC1N |
not identified |
2.17E-01 |
-1.91 |
50 |
not identified |
9 |
10 |
CC1CC(CC(O)(CC(C)=O)C(O)=O)CCC1N |
not identified |
4.90E-06 |
-2.83 |
58 |
not checked |
10 |
11 |
CC1CC(CC(O)(COC(C)=O)C(O)=O)CCC1N |
not identified |
5.44E-02 |
-2.22 |
56 |
not identified |
11 |
12 |
CC1CC(CC(O)(CO)C(O)=O)CCC1N |
not identified |
4.35E-06 |
-1.62 |
52 |
not checked |
12 |
13 |
CC1CC(CC(O)(C=O)C(O)=O)CCC1N |
not identified |
4.35E-06 |
-3.25 |
52 |
not checked |
13 |
14 |
CC1CC(CC(O)(C(O)=O)C(O)=O)CCC1N |
not identified |
4.48E-02 |
-3.59 |
50 |
not identified |
14 |
15 |
CC1CC(CC(=O)C(O)=O)CCC1N |
not identified |
3.91E-06 |
0.39 |
58 |
not checked |
15 |
16 |
CC1CC(CC(O)=O)CCC1N |
not identified |
3.91E-06 |
-1.48 |
56 |
not checked |
16 |
17 |
CC1CC(O)(CC(O)=O)CCC1N |
not identified |
1.25E-01 |
-2.98 |
54 |
not identified |
17 |
18 |
CC1CC(=O)CCC1N |
not identified |
9.95E-02 |
0.00 |
49 |
not identified |
18 |
19 |
CC1CC(=O)CCC1=O |
not identified |
1.66E-06 |
-0.51 |
77 |
not checked |
19 |
20 |
CC1CC(=O)CCC(=O)O1 |
not identified |
1.84E-02 |
0.85 |
76 |
not identified |
20 |
21 |
CC=CC(=O)CCC(O)=O |
not identified |
1.47E-06 |
0.57 |
85 |
not checked |
21 |
22 |
OC(=O)CCC(O)=O |
Succinic acid (CAS 110-15-8) |
1.52E-02 |
-0.75 |
90 |
not PBT/vPvB |
22 |
23 |
CCC(O)=O |
Propionic acid (CAS 79-09-4) |
1.35E-06 |
0.58 |
100 |
not checked |
23 |
26 |
CC=C |
Propene (CAS 115-07-1) |
1.47E-06 |
1.68 |
80 |
not checked |
24 |
27 |
CC1CO1 |
Methyloxirane (CAS 75-56-9) |
1.47E-06 |
0.37 |
77 |
not checked |
25 |
28 |
CC(O)CO |
1,2-Propanediol (CAS 57-55-6) |
1.47E-06 |
-0.78 |
73 |
not checked |
26 |
29 |
CC(O)C=O |
not identified |
1.47E-06 |
-1.21 |
73 |
not checked |
27 |
30 |
CC(O)C(O)=O |
D-lactic acid (CAS 10326-41-7) |
4.73E-02 |
-0.65 |
68 |
not PBT/vPvB |
28 |
31 |
CC=O |
Acetaldehyd (CAS 75-07-0) |
1.00E-06 |
-0.17 |
100 |
not checked |
29 |
32 |
CC(O)=O |
Acetic acid (CAS 64-19-7) |
1.61E-05 |
0.09 |
100 |
not checked |
30 |
34 |
CC1CC(CC2CCC(N)C(CO)C2)CCC1N |
not identified |
4.70E-07 |
2.64 |
48 |
not checked |
31 |
35 |
CC1CC(CC2CCC(N)C(C=O)C2)CCC1N |
not identified |
4.70E-07 |
2.61 |
48 |
not checked |
32 |
36 |
CC1CC(CC2CCC(N)C(C(O)=O)C2)CCC1N |
not identified |
6.61E-03 |
-0.34 |
46 |
not identified |
33 |
37 |
CC1CC(CC2CCC(N)C(C(O)=O)C2)CCC1=O |
not identified |
2.02E-07 |
-0.84 |
57 |
not checked |
34 |
38 |
CC1CC(O)(CC2CCC(N)C(C(O)=O)C2)CCC1=O |
not identified |
2.02E-07 |
-2.34 |
56 |
not checked |
35 |
39 |
CC1CC(O)(CC2CCC(N)C(C(O)=O)C2)CCC(=O)O1 |
not identified |
2.24E-03 |
-2.79 |
55 |
not identified |
36 |
40 |
CC(O)CC(O)(CCC(O)=O)CC1CCC(N)C(C(O)=O)C1 |
not identified |
1.79E-07 |
-3.06 |
62 |
not checked |
37 |
41 |
CC(O)CC(O)(CC1CCC(N)C(C(O)=O)C1)C=CC(O)=O |
not identified |
1.79E-07 |
-3.28 |
62 |
not checked |
38 |
42 |
CC(O)CC(O)(CC1CCC(N)C(C(O)=O)C1)C(O)CC(O)=O |
not identified |
1.79E-07 |
-4.60 |
61 |
not checked |
39 |
43 |
CC(O)CC(O)(CC1CCC(N)C(C(O)=O)C1)C(=O)CC(O)=O |
not identified |
1.79E-07 |
-4.20 |
61 |
not checked |
40 |
44 |
CC(O)CC(O)(CC1CCC(N)C(C(O)=O)C1)C(O)=O |
not identified |
5.51E-03 |
-3.74 |
55 |
not identified |
41 |
45 |
CC(=O)CC(O)(CC1CCC(N)C(C(O)=O)C1)C(O)=O |
not identified |
1.24E-07 |
-4.65 |
60 |
not checked |
42 |
46 |
CC(=O)OCC(O)(CC1CCC(N)C(C(O)=O)C1)C(O)=O |
not identified |
1.38E-03 |
-4.04 |
59 |
not identified |
43 |
47 |
NC1CCC(CC(O)(CO)C(O)=O)CC1C(O)=O |
not identified |
1.11E-07 |
-3.44 |
57 |
not checked |
44 |
48 |
NC1CCC(CC(O)(C=O)C(O)=O)CC1C(O)=O |
not identified |
1.11E-07 |
-5.08 |
57 |
not checked |
45 |
49 |
NC1CCC(CC(O)(C(O)=O)C(O)=O)CC1C(O)=O |
not identified |
1.14E-03 |
-4.82 |
55 |
not identified |
46 |
50 |
NC1CCC(CC(=O)C(O)=O)CC1C(O)=O |
not identified |
9.91E-08 |
-4.63 |
65 |
not checked |
47 |
51 |
NC1CCC(CC(O)=O)CC1C(O)=O |
not identified |
9.91E-08 |
-3.30 |
64 |
not checked |
48 |
52 |
NC1CCC(O)(CC(O)=O)CC1C(O)=O |
not identified |
3.18E-03 |
-4.81 |
62 |
not identified |
49 |
53 |
NC1CCC(=O)CC1C(O)=O |
not identified |
2.53E-03 |
-4.44 |
45 |
not identified |
50 |
54 |
OC(=O)C1CC(=O)CCC1=O |
not identified |
4.21E-13 |
-1.74 |
74 |
not checked |
51 |
55 |
OC(=O)C1CC(=O)OCCC1=O |
not identified |
2.10E-03 |
-0.39 |
67 |
not identified |
52 |
56 |
OC(=O)C1COC(=O)CCC1=O |
not identified |
2.10E-03 |
-0.39 |
78 |
not identified |
53 |
57 |
CC1CC(CC2CCC(=O)C(C(O)=O)C2)CCC1N |
not identified |
2.64E-03 |
-0.84 |
62 |
not identified |
54 |
58 |
CC1CC(CC(CCC(O)=O)CCC(O)=O)CCC1N |
not identified |
1.75E-12 |
-0.43 |
74 |
not checked |
55 |
59 |
CC1CC(CC(CCC(O)=O)C=CC(O)=O)CCC1N |
not identified |
1.75E-07 |
-0.65 |
74 |
not checked |
56 |
60 |
CC1CC(CC(CCC(O)=O)C(O)CC(O)=O)CCC1N |
not identified |
1.75E-07 |
-1.97 |
73 |
not checked |
57 |
61 |
CC1CC(CC(CCC(O)=O)C(=O)CC(O)=O)CCC1N |
not identified |
1.75E-07 |
-2.48 |
73 |
not checked |
58 |
62 |
CC1CC(CC(CCC(O)=O)C(O)=O)CCC1N |
not identified |
1.75E-07 |
-1.41 |
69 |
not checked |
59 |
63 |
CC1CC(CC(C=CC(O)=O)C(O)=O)CCC1N |
not identified |
1.75E-07 |
-1.63 |
69 |
not checked |
60 |
64 |
CC1CC(CC(C(O)CC(O)=O)C(O)=O)CCC1N |
not identified |
1.75E-07 |
-2.95 |
68 |
not checked |
61 |
65 |
CC1CC(CC(C(=O)CC(O)=O)C(O)=O)CCC1N |
not identified |
1.75E-07 |
-3.46 |
68 |
not checked |
62 |
66 |
CC1CC(CC(C(O)=O)C(O)=O)CCC1N |
not identified |
3.00E-04 |
-2.39 |
62 |
not checked |
63 |
67 |
CC1CC(CCC(O)=O)CCC1N |
not identified |
1.72E-07 |
-0.99 |
59 |
not checked |
64 |
68 |
CC1CC(C=CC(O)=O)CCC1N |
not identified |
1.72E-07 |
0.30 |
59 |
not checked |
65 |
69 |
CC1CC(C(O)CC(O)=O)CCC1N |
not identified |
1.72E-07 |
-2.53 |
57 |
not checked |
66 |
70 |
CC1CC(C(=O)CC(O)=O)CCC1N |
not identified |
1.72E-07 |
-3.04 |
57 |
not checked |
67 |
71 |
CC1CC(C(O)=O)CCC1N |
not identified |
6.47E-03 |
-1.97 |
46 |
not identified |
68 |
72 |
CC1CC(C(O)=O)CCC1=O |
not identified |
1.08E-07 |
0.72 |
77 |
not checked |
69 |
73 |
CC1CC(O)(C(O)=O)CCC1=O |
not identified |
1.08E-07 |
-0.47 |
76 |
not checked |
70 |
74 |
CC1CC(O)(C(O)=O)CCC(=O)O1 |
not identified |
1.20E-03 |
-0.92 |
74 |
not identified |
71 |
75 |
CC(O)CC(O)(CCC(O)=O)C(O)=O |
not identified |
9.57E-08 |
-1.19 |
96 |
not checked |
72 |
76 |
CC(O)CC(O)(C=CC(O)=O)C(O)=O |
not identified |
9.57E-08 |
-1.40 |
96 |
not checked |
73 |
77 |
CC(O)CC(O)(C(O)CC(O)=O)C(O)=O |
not identified |
9.57E-08 |
-1.53 |
95 |
not checked |
74 |
78 |
CC(O)CC(O)(C(=O)CC(O)=O)C(O)=O |
not identified |
9.57E-08 |
-2.32 |
95 |
not checked |
75 |
79 |
CC(O)CC(O)(C(O)=O)C(O)=O |
not identified |
2.94E-03 |
-2.17 |
93 |
not identified |
76 |
80 |
CC(=O)CC(O)(C(O)=O)C(O)=O |
not identified |
6.63E-03 |
-3.09 |
91 |
not identified |
77 |
82 |
CC1CC(CC2CC(C)C(N)CC(=O)O2)CCC1N |
not identified |
6.36E-04 |
1.60 |
42 |
not checked |
78 |
83 |
CC1CC(CC(O)CC(C)C(N)CC(O)=O)CCC1N |
not identified |
7.17E-04 |
-1.69 |
39 |
not checked |
79 |
84 |
CC1CC(CC(O)CC(C)C(N)CC(O)=O)CCC1=O |
not identified |
2.19E-08 |
-2.19 |
56 |
not checked |
80 |
85 |
CC(CC(O)CC1(O)CCC(=O)C(C)C1)C(N)CC(O)=O |
not identified |
2.19E-08 |
-3.29 |
55 |
not checked |
81 |
86 |
CC(CC(O)CC1(O)CCC(=O)OC(C)C1)C(N)CC(O)=O |
not identified |
2.43E-04 |
-3.74 |
53 |
not checked |
82 |
87 |
CC(CC(O)CC(O)(CCC(O)=O)CC(C)O)C(N)CC(O)=O |
not identified |
1.95E-03 |
-4.42 |
59 |
not identified |
83 |
88 |
CC1CC(CC(O)CC(C)C(=O)CC(O)=O)CCC1N |
not identified |
2.19E-08 |
-2.19 |
48 |
not checked |
84 |
89 |
CC1CC(CC(O)CC(C)C(O)=O)CCC1N |
not identified |
2.86E-04 |
-1.13 |
40 |
not checked |
85 |
90 |
CC1CC(CC(O)C=C(C)C(O)=O)CCC1N |
not identified |
1.90E-03 |
0.29 |
44 |
not identified |
86 |
91 |
CC1CC(CC2CCC(N)C(C)C(=O)O2)CCC1N |
not identified |
6.36E-04 |
1.60 |
33 |
not checked |
87 |
92 |
CC1CC(CC(O)CCC(N)C(C)C(O)=O)CCC1N |
not identified |
6.66E-04 |
-1.69 |
34 |
not checked |
88 |
93 |
CC1CC(CC(O)CCC(N)=C(C)C(O)=O)CCC1N |
not identified |
1.42E-03 |
-0.14 |
31 |
not identified |
89 |
94 |
CC=C(N)CCC(O)CC1CCC(N)C(C)C1 |
not identified |
1.13E-03 |
2.25 |
30 |
not identified |
90 |
95 |
CC=C(N)CCC(O)CC1CCC(=O)C(C)C1 |
not identified |
1.88E-03 |
1.74 |
46 |
not identified |
91 |
96 |
CC1CC(CC2CCC(N)C(C)OC2=O)CCC1N |
not identified |
6.36E-04 |
1.60 |
29 |
not checked |
92 |
97 |
CC1CC(CC(CCC(N)C(C)O)C(O)=O)CCC1N |
not identified |
1.56E-03 |
-1.69 |
30 |
not identified |
93 |
98 |
CC1CC(CC(CCC(N)C(C)=O)C(O)=O)CCC1N |
not identified |
1.13E-03 |
-1.44 |
33 |
not identified |
94 |
99 |
CC1CC(CCCCC(N)C(C)=O)CCC1N |
not identified |
3.38E-04 |
2.58 |
36 |
not checked |
95 |
100 |
CC1CC(CCCCC(N)C(C)=O)CCC1=O |
not identified |
1.03E-03 |
2.08 |
51 |
not identified |
96 |
101 |
CC1CC(CCCCC(=O)C(C)=O)CCC1N |
not identified |
1.03E-03 |
1.77 |
52 |
not identified |
97 |
102 |
CC1CC(CC2CC(C)C(N)COC2=O)CCC1N |
not identified |
6.36E-04 |
1.60 |
35 |
not checked |
98 |
103 |
CC1CC(CC(CC(C)C(N)CO)C(O)=O)CCC1N |
not identified |
1.63E-03 |
-1.69 |
38 |
not identified |
99 |
104 |
CC(CCCC1CCC(N)C(C)C1)C(N)CO |
not identified |
4.87E-04 |
2.33 |
37 |
not checked |
100 |
105 |
CC(CCCC1CCC(N)C(C)C1)C(=O)CO |
not identified |
1.49E-03 |
2.74 |
44 |
not identified |
101 |
106 |
CC(CCCC1CCC(=O)C(C)C1)C(N)CO |
not identified |
1.49E-03 |
1.83 |
56 |
not identified |
102 |
107 |
CC1CC(CC2CC(C)C(N)C(=O)OC2)CCC1N |
not identified |
8.07E-04 |
1.60 |
34 |
not checked |
103 |
108 |
CC1CC(CC2CC(C)C(N)C(=O)OC2)CCC1=O |
not identified |
2.46E-08 |
1.10 |
50 |
not checked |
104 |
109 |
CC1CC(CC2(O)CCC(=O)C(C)C2)COC(=O)C1N |
not identified |
2.46E-08 |
-0.41 |
48 |
not checked |
105 |
110 |
CC1CC(CC2(O)CCC(=O)OC(C)C2)COC(=O)C1N |
not identified |
2.73E-04 |
-0.86 |
47 |
not checked |
106 |
111 |
CC1CC(CC(O)(CCC(O)=O)CC(C)O)COC(=O)C1N |
not identified |
2.19E-08 |
-3.74 |
54 |
not checked |
107 |
112 |
CC1CC(CC(O)(CC(C)O)C=CC(O)=O)COC(=O)C1N |
not identified |
2.19E-08 |
-2.46 |
54 |
not checked |
108 |
113 |
CC1CC(CC(O)(CC(C)O)C(O)CC(O)=O)COC(=O)C1N |
not identified |
2.19E-08 |
-5.28 |
53 |
not checked |
109 |
114 |
CC1CC(CC(O)(CC(C)O)C(=O)CC(O)=O)COC(=O)C1N |
not identified |
2.19E-08 |
-4.87 |
53 |
not checked |
110 |
115 |
CC1CC(CC(O)(CC(C)O)C(O)=O)COC(=O)C1N |
not identified |
6.72E-04 |
-4.41 |
45 |
not checked |
111 |
116 |
CC1CC(CC(O)(CC(C)=O)C(O)=O)COC(=O)C1N |
not identified |
1.52E-03 |
-5.33 |
55 |
not identified |
112 |
117 |
CC1CC(CC2CC(C)C(=O)C(=O)OC2)CCC1N |
not identified |
2.73E-04 |
3.13 |
42 |
not checked |
113 |
118 |
CC1CC(CC(CC(C)C(=O)C(O)=O)CO)CCC1N |
not identified |
2.19E-08 |
1.23 |
42 |
not checked |
114 |
119 |
CC1CC(CC(CC(C)C(=O)C(O)=O)C=O)CCC1N |
not identified |
2.19E-08 |
1.21 |
42 |
not checked |
115 |
120 |
CC1CC(CC(CC(C)C(=O)C(O)=O)C(O)=O)CCC1N |
not identified |
2.25E-04 |
-2.32 |
40 |
not checked |
116 |
121 |
CC(CCCC1CCC(N)C(C)C1)C(=O)C(O)=O |
not identified |
9.82E-04 |
2.28 |
43 |
not checked |
117 |
122 |
CC1CC(CC(CC(C)C=O)C(O)=O)CCC1N |
not identified |
9.82E-04 |
-0.66 |
55 |
not checked |
118 |
123 |
CC1CC(CC2CC(C)C(N)OC(=O)C2)CCC1N |
not identified |
6.36E-04 |
3.35 |
40 |
not checked |
119 |
124 |
CC1CC(CC(CC(C)C(N)O)CC(O)=O)CCC1N |
not identified |
5.09E-08 |
-1.69 |
43 |
not checked |
120 |
125 |
CC1CC(CC(CC(C)C=O)CC(O)=O)CCC1N |
not identified |
5.09E-08 |
-0.17 |
43 |
not checked |
121 |
126 |
CC1CC(CC(CC(C)C(O)=O)CC(O)=O)CCC1N |
not identified |
5.09E-08 |
-0.50 |
41 |
not checked |
122 |
127 |
CC1CC(CC(O)(CC(C)C(O)=O)CC(O)=O)CCC1N |
not identified |
6.66E-04 |
-2.01 |
39 |
not checked |
123 |
128 |
CC1CC(CC(O)(CC(O)=O)C=C(C)C(O)=O)CCC1N |
not identified |
5.79E-04 |
-2.09 |
47 |
not checked |
124 |
129 |
CC1CC(CC(O)(CC(O)=O)C(O)C(C)C(O)=O)CCC1N |
not identified |
5.03E-04 |
-3.14 |
44 |
not checked |
125 |
130 |
CC1CC(CC(O)(CC(O)=O)C(O)=C(C)C(O)=O)CCC1N |
not identified |
3.35E-08 |
-2.57 |
55 |
not checked |
126 |
131 |
CC1CC(CC(O)(CC(O)=O)C(=O)C(C)C(O)=O)CCC1N |
not identified |
4.38E-04 |
-3.14 |
55 |
not checked |
127 |
132 |
CC1CC(CC(O)(CC(O)=O)C(O)=O)CCC1N |
not identified |
9.33E-04 |
-2.79 |
50 |
not checked |
128 |
133 |
CC1CC(CC(=O)CC(O)=O)CCC1N |
not identified |
1.98E-03 |
-2.55 |
64 |
not identified |
(metabolites which are predicted at quantity >0.001 after 28 d are highlighted in grey and written in bold letters)
(metabolite no: according to (Q)SAR model CATALOGIC 301C v11.15 – July 2018 (OASIS CATALOGIC v5.13.1.156))
Conclusion:
The parent (DMDC (CAS 6864 -37 -5) as well as its relevant metabolites are not expected to significantly accumulate in organisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.