Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 615-064-0 | CAS number: 700874-87-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Because of the physico-chemical properties and conditions of use of the substance inhalation is the most likely route of exposure for human.
An acute toxicity study conducted by inhalation showed that 4 hour-exposure to MOVE 3 vapours at the concentration of 20.65 mg/L did not cause any mortality and adverse effects on rat.
No studies are available of acute toxicity by oral and dermal routes.
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because a study on acute toxicity by the inhalation route is available
- other:
- Reason / purpose for cross-reference:
- data waiving: supporting information
- Reason / purpose for cross-reference:
- data waiving: supporting information
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Quality of whole database:
- no studies of acute toxicity by oral route are available.
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- discriminating conc.
- Value:
- 20 650 mg/m³ air
- Quality of whole database:
- One study on the test item is available. This study was conducted according to standard OECD guideline and in compliance with GLP. The study is suitable for the assessment of acute toxicity via inhalation, the overall quality of the dataset for acute toxicity by inhaltion is therefore considered to be good.
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Quality of whole database:
- no studies of acute toxicity by dermal route are available.
Additional information
The substance is a very volatile low boiling point liquid (BP 19.5 °C, VP =97 kPa.at 20°C), only used in industrial applications where oral exposure is not anticipated and operational and engineering controls are in place in order to control human exposure by dermal and inhalation routes. Considering the physico-chemical properties of the substance and its uses, inhalation is the most likely route of exposure therefore testing by oral and dermal route is considered not necessary.
An acute inhalation toxicity study conducted according to OECD guideline 403 and in compliance with good laboratory practices (GLP) is available.
A group of five male and five female albino rats was exposed for a single 4-hour period to a vapour of the MOVE 3 at a chemically determined mean atmosphere concentration of 20.65 ± 0.55 mg/L air. There were no deaths, no clinical signs and no macroscopic pathology findings. Body weight was not adversely affected in male animals. Minor effects on female body weight was observed but the relationship of these effects to treatment with the test item is unclear.
The median lethal concentration (LC50, 4h) of the test substance is concluded to be higher than 20.65 mg/L for male and female rats.
Justification for classification or non-classification
The median lethal concentration (LC50, 4h) of the test substance is higher than 20.65 mg/L for male and female rats, therefore the test substance does not meet the classification criteria of EC Regulation No. 1272/2008 (CLP / EU GHS).
As no mortality and significant signs of toxicty were observed up to the concentrations of 20 mg/L, the substance does not fullfill the classification criteria according to UN GHS Category 5 criteria for acute toxicity by inhalation.
Moreover, no sign of impairment was observed in any investigated organ therefore MOVE 3 does not require STOT SE classification (inhalation) according to Regulation (EC) No. 1272/2008 (CLP / EU GHS) and UN GHS criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.