Xanthylium, 9-[2-(ethoxycarbonyl)phenyl]-3,6-bis(ethylamino)-2,7-dimethyl-, molybdatetungstatephosphate

PBT assessment

PBT assessment: overall result

PBT status:

the substance is not PBT / vPvB

Justification:

Classification of Xanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, molybdatetungstatephosphate for effects in the environment:

 

The chemicalXanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, molybdatetungstatephosphate(CAS no. 12224-98-5) is used in colour printing inks. They are mostly used in interior paints with special lustrous appearance, foil lacquers, poster paints and enamels. Also used as a coloration in plastics, leather and other industries. The aim was to assess whether the PBT criterion within Annex XIII was fulfilled forXanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, molybdatetungstatephosphate. The PBT criterion was herein assessed based on experimental data in conjunction with standardized environmental fate models. Here follows a description of the PBT assessment.

 

Persistence assessment

The tested substance fulfils the P criterion within Annex XIII based on the assessment that here follows:

 

Biotic degradation

Biodegradability of test chemical Xanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, molybdatetungstatephosphate (CAS no. 12224 -98 -5) was determined by using OECD QSAR tool box v3.3 and five closest red across chemical with log Kow as primary descriptor. Percent biodegrdation of test chemical Xanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, molybdatetungstatephosphate was determined to be 6.16 % by considering BOD as parameter  and microrganisms as inoculum in 28 days.

 

Estimation Programs Interface Suite (EPI suite, 2017) was run to predict the biodegradation potential of the test compound  Xanthylium, 9 -(2 -(ethoxycarbonyl)phenyl)-3,6 -bis(ethylamino)-2,7 -dimethyl-, molybdatetungstatephosphate (CAS no. 12224 -98 -5) in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical Xanthylium, 9 -(2 -(ethoxycarbonyl)phenyl)-3,6 -bis(ethylamino)-2,7 -dimethyl-, molybdatetungstatephosphate is expected to be not readily biodegradable.

                                                                 

Experimental results from the read across substances (CAS: 81-88-9 and 518-47-8) also indicate that they are not readily biodegradable.

 

Environmental fate

According to the fugacity model levels III, the most likely environmental fate for this test chemical is sediment (i.e. estimated to 57.7%). The half-life in sediment (541.66 days estimated by EPI suite) indicates that the chemical is verypersistent in sediment and the exposure risk is moderate to high. 

If released in to the environment, 41.1% of the chemical will partition into soil according to the Mackay fugacity model level III in EPI suite version 4.1 (2017).In soil,Xanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, molybdatetungstatephosphatewas expected to have negligible mobility based upon a Log Koc value of 7.206, respectively.However, the half-life (120 days estimated by EPI suite) indicates that the chemical isnot persistent in soil and the exposure risk to soil dwelling animals is moderate to low.

 

Moreover, its persistent characteristic is also observed in the water compartment according to the Mackay fugacity model level III in EPI suite version 4.1 (2017) with a half-life value of 60 days. This half-life value indicates that the chemical is persistent in water and the exposure risk to aquatic animals is moderate to high. 

 

Although the half-life values indicate the chemical to be Very persistent (vP), since only predicted data is available for the substance, it has been concluded thatXanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, molybdatetungstatephosphateis likely to be persistent in nature.

 

 

Bioaccumulation assessment

The tested substance fulfils the B criterion within Annex XIII based on the assessment that here follows:

 

The estimated BCF value from authoritative database was determined to be 8131 L/Kg, respectively and the octanol water partition coefficient of the test chemical is 7.4364 which is greater than the threshold of 4.5. If this chemical is released into the aquatic environment, there should be a high risk for the chemical to bioaccumulate in fish and food chains.

 

Although the BCF value indicate the chemical to be Very bioaccumulative (vB), since only predicted data is available for the substance, it has been concluded thatchemicalXanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, molybdatetungstatephosphateis bioaccumulative (B) infish and food chains.

 

Toxicity assessment

The tested substance does not fulfil the T criterion within Annex XIII based on the assessment that here follows:

 

Mammals

The tested chemical is regarded to be not classified for carcinogenicity, mutagenicity and reprotoxicity, Further, there is no evidence of chronic toxicity, as identified by the classifications STOT (repeated exposure), category 1(oral, dermal, inhalation of gases/vapours, inhalation of dust/mist/fume) or category 2 (oral, dermal, inhalation of gases/vapours, inhalation of dust/mist/fume).

 

Aquatic organisms

All of the available short-term eco-toxicity estimations for fish, invertebrates and algae for the substance indicates the LC50/EC50 value to be in the range 137.827 – 935.79 mg/L, respectively. These value suggest that the substance is not likely to be hazardous to Aquatic organisms at environmentally relevant concentrations and can be considered to be ‘not classified’ as per the CLP regulation.

 

By speculation, long-term NOEC for aquatic organisms were not expected for the substanceXanthylium, 9-(2-(ethoxycarbonyl)phenyl)-3,6-bis(ethylamino)-2,7-dimethyl-, molybdatetungstate phosphate at concentration below 0.01 mg/L based on the data mentioned above

 

The chemical was therefore not considered as hazardous to aquatic environments as per the criteria set out in Annex XIII.

 

Conclusion

Based on critical, independent and collective evaluation of information summarized herein, the tested compound fulfils the P and B criterion but does not fulfil the T criterion and has therefore not been classified as a PBT compound within Annex XIII.