Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 240-968-3 | CAS number: 16919-19-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Study completion date - 01 January 2010.
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Remarks:
- data owner contacted; so far the LR did not provide the full study report
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Name: Sodium hexafluorosilicate
- Analytical monitoring:
- yes
- Details on sampling:
- The samples of the concentration levels 6.25 to 100 mg/L and the pH control were diluted with double distilled water prior to analysis.
- Vehicle:
- no
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- 20 daphnids, divided into 4 replicates, each with 5 daphnids per concentration level, pH-control and control. 2 to 24 h old daphnids were used for the study.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 244 mg CaCO3/L
- Test temperature:
- 18 - 22 °C, ± 1 °C constant
- pH:
- pH=8. The highest test concentration of 100 mg/L was adjusted to a pH in the range 7.0 ± 0.2 by addition of 1 M NaOH and tested under the same conditions as the test and control groups. Additionally, a pH-control was included in the test series, because the highest test concentration showed a pH-value of 3.55, which is outside the recommended range of pH 6 to 9.
- Dissolved oxygen:
- The dissolved O2 concentration was >3 mg/L: 8.30 mg/L
- Salinity:
- 0.1%
- Nominal and measured concentrations:
- Nominal concentrations: 6.25 - 12.5 - 25.0 - 50.0 - 100 mg/L, prepared with dilution water.
- Details on test conditions:
- Illumination: Diffuse light, illumination strength max. 20 µE.m-2.s-1; Photoperiod: 16/8 h light/dark cycle; Feeding: The daphnids were not fed during the study.
- Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 35.4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 25 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- LOEC
- Effect conc.:
- ca. 50 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- Daphnids were exposed to disodium hexafluorosilicate in water solutions of concentrations of 6.25 - 12.5 - 25.0 - 50.0 - 100 mg/L. EC100-values after 24 and 48 h, the NOEC and LOEC after 48 h were deduced directly from the observation data without mathematical calculation.
- Validity criteria fulfilled:
- yes
- Conclusions:
- EC50=35.4 mg/l; NOEC= 25 mg/l; LOEC= 50 mg/l.
- Executive summary:
Sodium hexafluorosilicate was evaluated for short term toxicity to aquatic invertebrates in a study conducted according to OECD Guideline 202. 2 to 24 h old daphnids were used for the study. 20 daphnids, divided into 4 replicates, each with 5 daphnids per concentration level, were exposed to nominal concentrations of 6.25, 12.5, 25.0, 50.0 and 100 mg/L for 48 hours only. While, no immobility was recorded at the concentrations of 6.25, 12.5 and 25.0 mg/l, 100 % immobility was recorded at 50 and 100 mg/l concentrations.
Based on these findings, sodium hexafluorosilicate was estimated to have 48 hour EC50 of 35.4 mg/l, while NOEC and LOEC were 25 and 50 mg/l, respectively.
Reference
Table: Observations of mobility
Nominal concentration |
IMMOBILIZATION [%] |
|||||||||
24 h |
48 h |
|||||||||
Replicates |
Replicates |
|||||||||
[mg/L] |
1. |
2. |
3. |
4. |
MV |
1. |
2. |
3. |
4. |
MV |
100 (pH control)* |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
50.0 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
100 |
25.0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
12.5 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
6.25 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
Control |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 35.4 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.