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Diss Factsheets
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EC number: 223-892-5 | CAS number: 4111-08-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Skin contact: Immediately remove contaminated clothing. Wash contaminated skin with large quantities of (preferably lukewarm) water. If poisoning symptoms appear, follow the above instructions for inhalation exposure. Obtain medical help immediately!
Eye contact: Immediately flush eyes with large quantities of water for 10-15 minutes. While flushing, keep eyelids open even by using force. Obtain medical help immediately!
Ingestion: Obtain medical help immediately! Ingestion of even small amounts is likely to be fatal unless treated rapidly.
Protect yourself and any casualty from further exposure during providing first aid (can be affected also the protective clothing). Wear specified PPE until test confirms no further risk from exposure.
Fire-fighting measures
Unsuitable extinguishing media are following: alkali substances since they accelerate the decomposition of product to HCN and butanone.
Use protective chemical suit and self-contained breathing apparatus.
Accidental release measures
Prevent further leakage. Avoid penetration to soil, water, sewerage. If the substance penetrates into river or water reservoir, inform the users, stop operation and using the water.
If possible, pump spilled MEKH into a safe container. Vapor, gas shall be condensed using mist. Prevent fire and sparks. Puddles covered with a suitable absorbent material (sorbent, sand, sawdust) and collect into a suitable container marked for further processing or disposal in accordance with local legislation. Spray the contaminated area with diluted sodium hydroxide and subsequently with diluted solution of sodium hypochlorite. In case MEKH penetrated into soil, it is necessary to remove all the contaminated soil and decontaminate it in designed place.
Handling and storage
To be stored separately in original sealed packaging units in dry, cool locked storerooms. The storage area must be free of acids and alkali reacting substances, as they carry the risk of releasing highly toxic hydrogen cyanide.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 3276
Shipping information
- Proper shipping name and description:
- NITRILES, TOXIC, LIQUID, N.O.S.
- Chemical name:
- 2-hydroxy-2-methylbutyronitrile
- Language:
- English
- Labels:
- 6.1
Special provisions / remarks
- Remarks:
- Use label for environmentally hazardous substance.
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 3276
Shipping information
- Proper shipping name and description:
- NITRILES, TOXIC, LIQUID, N.O.S.
- Chemical name:
- 2-hydroxy-2-methylbutyronitrile
- Language:
- English
- Labels:
- 6.1
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 3276
Shipping information
- Proper shipping name and description:
- NITRILES, TOXIC, LIQUID, N.O.S.
- Chemical name:
- 2-hydroxy-2-methylbutyronitrile
- Labels:
- 6.1
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 3276
Shipping information
- Proper shipping name and description:
- NITRILES, TOXIC, LIQUID, N.O.S.
- Chemical name:
- 2-hydroxy-2-methylbutyronitrile
- Labels:
- 6.1
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
2. Organisational protection measures: It must be ensured the action of 2 workers (so called the buddy system).
3. Hand protection: Gloves- material PVC, thickness min 0.35 mm, penetration time > 30 min
4. Feet protection: Boots
5. Body protection: PVC-coated protective clothing
6. Eye protection: Face mask with antigas filter type B2 or its equivalent (e.g. combined filter A2B2E2K2P3D), self-contained breathing apparatus and/or eye protection.
7. Respiratory protection: Face mask with antigas filter type B2 or its equivalent (e.g. combined filter A2B2E2K2P3D), self-contained breathing apparatus
Stability and reactivity
Stable in acidic environment. In alcalic environment decomposes into butanon and hydrogen cyanide.
Possibilities of hazardous reactions are not known.
Avoid to direct sunlight, heat and air humidity.
Incompatible materials are following: Strong acids, strong alkalis, oxidising agents, reducing agents, water.
During decomposition can be formed hydrogen cyanide (HCN) and butanone.
Disposal considerations
Recommended waste classification according to the manufacturer according to Decree no. 381/2001 Coll. as amended :
160 305 * - organic waste containing dangerous substances
150110 * - packaging contaminated by hazardous substances
Do not let the product enter sewerage.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.