Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-622-8 | CAS number: 144-29-6
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Justification for type of information:
- data from modelling database
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: predicted data
- Principles of method if other than guideline:
- To estimate the partition coefficient of the test chemical using KOWWIN model from EPISUITE
- GLP compliance:
- not specified
- Type of method:
- other: predicted data
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Piperazine citrate / tripiperazine dicitrate- Molecular formula: C12H30N6•Cl2H16O14 - Molecular weight: 642.76 g/mole - Substance type: Organic - Physical state: Solid
- Analytical method:
- not specified
- Key result
- Type:
- log Pow
- Partition coefficient:
- -1.15
- Remarks on result:
- other: no additional details mentioned
- Conclusions:
- The octanol water partition coefficient of the test chemical was estimated using KOWWIN model from EPISUITE. The estimated log Pow of piperazine citrate was -1.15.
- Executive summary:
The octanol water partition coefficient of the test chemical was estimated using KOWWIN model from EPISUITE.
The estimated logPow of piperazine citrate was -1.15.
Based on this value, piperazine citrate can be considered to be hydrophillic in nature, which is also supported by the water solubility of the test chemical.
Reference
Description of key information
The octanol water partition coefficient of the test chemical was estimated using KOWWIN model from EPISUITE. The estimated log Pow of piperazine citrate was -1.15.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -1.15
Additional information
The octanol water partition coefficient of the test chemical was estimated using KOWWIN model from EPISUITE. The estimated logPow of piperazine citrate was -1.15. Based on this value, piperazine citrate can be considered to be hydrophillic in nature, which is also supported by the water solubility of the test chemical.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
