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EC number: 281-619-5 | CAS number: 84000-63-5
Endpoint summary
Administrative data
Description of key information
Stability
Hydrolysis
The hydrolysis study of disodium 2-[[5-carbamoyl-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl] azo]-4-[[4-chloro-6-[[3- [[2-(sulphonatooxy)ethyl] sulph onyl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulphonate was predicted using OECD QSAR toolbox version 3.3 (2017) to predict the hydrolysis half-life of test compound disodium 2-[[5-carbamoyl-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl] azo]-4-[[4-chloro-6-[[3-[[2-(sulphonatooxy)ethyl]sulphonyl]phe nyl] amino]-1,3,5-triazin-2-yl]amino]benzenesulphonate (CAS No.84000-63-5).The half-life of disodium 2-[[5-carbamoyl-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6- oxo-3-pyridyl] azo]-4-[[4-chloro-6-[[3-[[2-(sulphonatooxy)ethyl] sulphonyl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulphonate was estimated to be 146.31 days at temperature 25 degC, indicating that the substance disodium 2-[[5-carbamoyl-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl] azo]-4-[[4-chloro- 6-[[3-[[2-(sulphonatooxy)ethyl]sulphonyl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulphonate is not hydrolysable.
Additional information
Stability
Hydrolysis
In a different studies,disodium 2-[[5-carbamoyl-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl] azo]-4-[[4-chloro-6-[[3-[[2-(sulphonatooxy)ethyl]sulphonyl] phenyl]amino]-1,3,5-triazin-2-yl]amino]benzene sulphonate(CAS No.84000-63-4) has been investigated for its hydrolysis potential to a greater or lesser extent. These include predicted and experimental study for target substancedisodium 2-[[5-carbamoyl-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl] azo]-4- [[4-chloro-6-[[3-[[2-(sulphonatooxy)ethyl] sulphonyl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulphonate (CAS No.84000-63-5) and for its closest read across substance disodium 6-hydroxy-5-[(2-methoxy-4-sulphonato-m-tolyl)azo]naphthalene-2-sulphonate (CAS No.- 25956 -17 -6) by considering its structure-activity relationships, were reviewed and are summarized as follows:
The hydrolysis study of disodium 2-[[5-carbamoyl-1-ethyl-1,6-dihydro-2-hydroxy-4 -methyl-6-oxo-3-pyridyl] azo]-4-[[4-chloro-6-[[3- [[2-(sulphonatooxy)ethyl] sulph onyl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benz enesulphonate was predicted using OECD QSAR toolbox version 3.3 (2017) to predict the hydrolysis half-life of test compound disodium 2-[[5-carbamoyl-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl] azo]-4-[[4-chloro-6-[[3-[[2-(sulphonatooxy)ethyl]sulphonyl]phe nyl]amino]-1,3,5-triazin-2-yl]ami no]benzenesulphonate (CAS No.84000-63-5).The half-life of disodium 2-[[5-carbamoyl-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6- oxo-3-pyridyl] azo]-4-[[4-chloro-6-[[3-[[2-(sulphonatooxy)ethyl] sulphonyl] phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulphonate was estimated to be 146.31 days at tempe rature 25 degC, indicating that the substance disodium 2-[[5-carbamoyl-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl] azo]-4-[[4-chloro- 6-[[3-[[2-(sulphonatooxy)ethyl]sulphonyl] phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulphonate is not hydrolysable.
Supported by the study from an authoritative database (Hazardous Substances Data Bank (HSDB, 2017) for a read across substance disodium 6-hydroxy-5- [(2-methoxy-4-sulphonato-m-tolyl)azo]naphthalene-2-sulphonate (CAS No.- 25956 -17 -6).The substance disodium 6-hydroxy-5-[(2-methoxy-4-sulphonato -m- tolyl)azo]naphthalene-2-sulphonate (Allura Red AC dye) (CAS No.- 25956 -17 -6) is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions.
Based on the above available studies for the target and read across substance, it can be concluded that the test substance disodium 2-[[5-carbamoyl-1- ethyl- 1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl] azo]-4-[[4-chloro-6-[[3-[[2 -(sulphonatooxy)ethyl]sulphonyl]phenyl]amino]-1,3,5-triazin-2-yl] amino] benzenesulphonate (CAS No.84000-63-5) is not expected to undergo hydrolysis in the environment i.e., it is not hydrolysable.
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