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Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to microorganisms, other
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Justification for type of information:
Data is from secondary source.
Qualifier:
no guideline available
Principles of method if other than guideline:
Study of toxicity to microorganisms was carried out.
GLP compliance:
not specified
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Tetrahymena pyriformis
Test type:
static
Water media type:
freshwater
Total exposure duration:
48 h
Reference substance (positive control):
not specified
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
7.49 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: Other details not known
Validity criteria fulfilled:
not specified
Conclusions:
On the basis of toxicity to microorganisms (Tetrahymena pyriformis) the 48 hr EC50 value was determined to be 7.49 mg/l.
Executive summary:

The study of toxicity to microorganisms was carried out. The duration of study was 48 hr performed under static conditions. Tetrahymena piriformis was taken as microorganism. On the basis of toxicity to microorganisms (Tetrahymena pyriformis) the 48 hr EC50 value was determined to be 7.49 mg/l. As per the value of EC50 the test chemical was consider as toxic to microorganism. 

Description of key information

On the basis of toxicity to microorganisms (Tetrahymena pyriformis) the 48 hr EC50 value was determined to be 7.49 mg/l.

Key value for chemical safety assessment

EC50 for microorganisms:
7.49 mg/L

Additional information

Different experimental studies for the toxicity to microorganisms endpoint were reviewed for the test substance  and are summarised below:


 


The first study of toxicity to microorganisms was carried out. The duration of study was 48 hr performed under static conditions. Tetrahymena piriformis was taken as microorganism. On the basis of toxicity to microorganisms (Tetrahymena pyriformis) the 48 hr EC50 value was determined to be 7.49 mg/l. As per the value of EC50 the test chemical was consider as toxic to microorganisms. 


 


The second study of toxicity to microorganisms was carried out. The duration of test was 30 min and was performed under static conditions. Photobacterium phosphoreum was taken as test organism. On the basis of toxicity to microorganisms (Photobacterium phosphoreum ) the 30 min EC50 value was determined to be 8.9 mg/l. As per the value of EC50 the test chemical was consider as toxic to microorganism. 


 


The third study of toxicity to microorganisms was carried out. The duration of study was 35 hr performed under static conditions. Tetramitus rostratus was taken as microorganism. On the basis of toxicity to microorganisms (Tetramitus rostratus) the 35 hr EC50 value was determined to be  > 1 to < 17 mg/l. As per the value of EC50 the test chemical was consider as toxic to microorganisms. 


 


On the basis of above-mentioned information, the test chemical was considered toxic to microorganisms.