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EC number: 211-448-3 | CAS number: 645-62-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with acceptable restriction (e.g. non-GLP, no analytical verification of test item concentrations, solubiliser used)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1988
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 79/831/EEC, Annex V, Part C2
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-ethylhex-2-enal
- EC Number:
- 211-448-3
- EC Name:
- 2-ethylhex-2-enal
- Cas Number:
- 645-62-5
- Molecular formula:
- C8H14O
- IUPAC Name:
- 2-ethylhex-2-enal
- Details on test material:
- - Name of test material (as cited in study report): 2-Ethylhexen-2-al crude
- Analytical purity: >= 95 %)
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: the test substance (100 mg/l) was dispersed with Tween 80 (100 mg/l; 95 %; Merck) in the test medium
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): Tween 80
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Source: originally supplied from "Institut National de Recherche Chimique appliquee, France", bred since 1978 at BASF
- Age at study initiation (mean and range, SD): 2-24 h
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 18.9-20.9 °C
- pH:
- 7.52 - 7.99
- Dissolved oxygen:
- 7.27 - 8.85
- Nominal and measured concentrations:
- Nominal test concentrations: 0 (control + solvent control), 1.563, 3.13, 6.25, 12.5, 25, 50, 100 mg/l
- Details on test conditions:
- TEST SYSTEM
- Test vessel: glass tubes with flat bottom
- Fill volume: 10 ml (2 ml/animal)
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: artificial freshwater: chlorine-free filtered tapwater supplemented with H2SO4 for the reduction of the buffering capacity of the carbonic acid system, and with deionized water for the reduction of the total hardness (total hardness: 2.70 +- 0.5 mmol/l, acid capacity to pH 4.3: 0.80 +- 0.10 mmol/l; molar ratio Ca:Mg = 4:1; molar ratio of Na:K = 10:1; conductivity: 550-650 µSiemens/cm; pH 7.7-8.3); aerated till saturation with oil-free air and allowed to stabilize for 24 h
- Intervals of water quality measurement: pH and dissolved oxygen: after 0 and 48 h
OTHER TEST CONDITIONS
- Light intensity: diffuse light
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Mobility after 0, 3, 6, 24 and 48 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 12.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 20.04 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 50 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Reported statistics and error estimates:
- The EC50 values were calculated using the moving average method
Any other information on results incl. tables
Effect values (mg/l; 95 % confidence interval):
24 h 48 h
EC 0: 12.5 12.5
EC 50: 22.75 (9.24-36.26) 20.04 (12.2-27.88)
EC 100: 50 50
Immobility:
Nominal Cumulative immobility (n)
Concentration (mg/l) 0 h 3 h 6 h 24 h 48 h
0 (control) 0 1 1 1 1
0 (solvent control) 0 0 0 0 0
1.563 0 0 0 0 0
3.13 0 0 0 0 0
6.25 0 0 0 0 0
12.5 0 0 0 0 1
25 0 0 5 14 6
50 0 15 15 20 20
100 0 20 20 20 20
The results were obtained at 19.0 °C (test start), while the
test medium had the following specifications:
pH 8.0
Total hardness: 2.88 mmol/l
Acid capacity to pH 4.3: 0.85 mmol/l
Nominal pH oxygen (mg/l)
Concentration (mg/l) 0 h 48 h 0 h 48 h
0 (control) 7.99 7.82 8.85 8.65
0 (solvent control) 7.82 7.61 8.89 7.63
1.563 7.95 7.83 8.70 8.73
3.13 7.93 7.78 8.63 8.52
6.25 7.93 7.76 8.70 8.39
12.5 7.90 7.67 8.85 7.67
25 7.86 7.67 8.73 8.22
50 7.79 7.6 8.75 8.02
100 7.72 7.52 8.78 7.27
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.