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EC number: 432-240-0 | CAS number: 12056-51-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 January 1999 to 4 May 1999.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in compliance with agreed protocols, with no or minor deviations, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EEC, A3 (Gas comparison: Pycnometer method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Date of inspection: 23/03/1998 Date of signature: 21/07/1998
- Type of method:
- pycnometer method
- Type:
- relative density
- Density:
- 3.5 other: (corresponds to D4(20))
- Temp.:
- 20 °C
- Conclusions:
- The relative density was determined to be 3.50 at 19.5 ± 0.5°C, using a gas comparison pycnometer, Method A3 of Commission Directive 92/69/EEC.
- Executive summary:
The relative density was determined to be 3.50 at 19.5 ± 0.5°C, using a gas comparison pycnometer, Method A3 of Commission Directive 92/69/EEC.
- Endpoint:
- tap density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- No data
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Process was carried out in own analytical laboratory under internal quality procedure
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- Deviations:
- yes
- Remarks:
- internal procedure based on above standard
- Principles of method if other than guideline:
- The tapped density is an increased bulk density after mechanically tapping a container containing the powder sample. Tapped density is obtained by tapping a graduated measuring cylinder or vessel containing a powder sample. After observing the initial volume or weight, the measuring cylinder or vessel is mechanically tapped, and volume or weight readings are taken until little further volume or weight change is observed. The mechanical tapping is achieved by raising the cylinder or vessel and allowing it to drop under its own weight by a specified distance
The bulk specific gravity is calculated from the capacity and the mass of a sample filled by "Tap Denser".
At first the sample is pre-processed by a sieve of opening size 850μm, and, of these, the sample of approximately 50g is put in the measuring cylinder. Furthermore, this is set in The Tap Denser and is tapped 50 times in 25sec.
After tapping, the capacity and mass are measured, and specific gravity is calculated.
Bulk specific gravity (g/cm3) = Mass (g) / Capacity (cm3) - GLP compliance:
- no
- Type of method:
- other: tap density method for powders
- Type:
- tap density
- Density:
- > 3.4 - < 3.6 g/cm³
- Temp.:
- 20 °C
- Conclusions:
- Specific gravity of the Tofix-S is between 3.4 and 3.6 g/cm³
- Endpoint:
- density
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- other: Information provided by Toho Material
- Qualifier:
- no guideline available
- Guideline:
- other: Tap density method
- Principles of method if other than guideline:
- The tapped density is an increased bulk density after mechanically tapping a container containing the powder sample. Tapped density is obtained by tapping a graduated measuring cylinder or vessel containing a powder sample. After observing the initial volume or weight, the measuring cylinder or vessel is mechanically tapped, and volume or weight readings are taken until little further volume or weight change is observed.
- GLP compliance:
- not specified
- Type of method:
- other: Bulk specific gravity
- Endpoint:
- density
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- other: Information provided by Toho Material
- Principles of method if other than guideline:
- The tapped density is an increased bulk density after mechanically tapping a container containing the powder sample. Tapped density is obtained by tapping a graduated measuring cylinder or vessel containing a powder sample. After observing the initial volume or weight, the measuring cylinder or vessel is mechanically tapped, and volume or weight readings are taken until little further volume or weight change is observed.
- GLP compliance:
- not specified
- Type of method:
- other: Bulk specific gravity
Referenceopen allclose all
Bulk specific gravity: 1.1~1.5g/cm3
Bulk specific gravity: 0.9~1.3g/cm3
Description of key information
The relative density was determined to be 3.50 at 19.5 ± 0.5°C, using a gas comparison pycnometer, Method A3 of Commission Directive 92/69/EEC. In another study the specific gravity of the substance (Tofix-S) was between 3.4 and 3.6 g/cm³.
The bulk specific gravity depends on the particle size of the manufactured material:
Tofix-SNR (Large Particle Size) = 1.1~1.5g/cm³
Tofix-SNR (Small Particle Size) = 0.9~1.3g/cm³
Key value for chemical safety assessment
- Relative density at 20C:
- 3.5
Additional information
The relative density was determined to using a gas comparison pycnometer, Method A3 of Commission Directive 92/69/EEC.
The test described above meet the requirements of OECD Test Guidelines and are assigned to be reliability 1 data according to the scoring system of Klimisch et al (Klimischet al., 1997). This ranking was deemed appropriate because the studies were conducted at the GLP certified laboratory and were in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results.
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