Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 811-616-1 | CAS number: 1563063-07-9
Endpoint summary
Administrative data
Description of key information
Skin sensitisation (OECD 442B): skin sensitising
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
The skin sensitising potential of the test substance was investigated in a Local Lymh Node Assay (LLNA) performed according to OECD Guideline 442B and in compliance with GLP (2017).
Treatment of CBA/N mice with the test substance revealed stimulation indices of 1.03, 1.01, 2.17, 3.06 and 3.09 at test substance concentrations of 1, 10, 25, 50 and 100% (w/v) in acetone/olive oil (4:1 v/v), respectively. The EC1.6 value was calculated to be 16.7%.
In conclusion, based on the available data the test substance is considered to be a weak skin sensitiser.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
The available data on skin sensitisation meets the criteria for classification as Skin Sens 1B (H317) according to Regulation (EC) 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
