Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 206-496-7 | CAS number: 350-03-8
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
Water Solubility:
1) 42,670 mg/L (25°C, very soluble (> 10000 mg/L), QSAR estimation using WSKOW v1.42 (EPIWIN software) by US-EPA)
2) 1,000,000 mg/L (25°C, very soluble (> 10000 mg/L), QSAR estimation using WATERNT v1.01 (EPIWIN software) by US-EPA)
3) soluble (no information on temperature and pH, peer-reviewed database)
4) QSAR estimation using the ACD Labs software v11.02:
Mass Intrinsic Solubility : Soluble (28 g/L) , Temp: 25 °C
Mass Solubility : Very Soluble (1000 g/L) , pH 1, Temp: 25 °C
Mass Solubility : Very Soluble (709 g/L) , pH 2, Temp: 25 °C
Mass Solubility : Very Soluble (100 g/L) , pH 3, Temp: 25 °C
Mass Solubility : Soluble (35 g/L) , pH 4, Temp: 25 °C
Mass Solubility : Soluble (28 g/L) , pH 5, Temp: 25 °C
Mass Solubility : Soluble (28 g/L) , pH 6, Temp: 25 °C
Mass Solubility : Soluble (28 g/L) , pH 7, Temp: 25 °C
Mass Solubility : Soluble (28 g/L) , pH 8, Temp: 25 °C
Mass Solubility : Soluble (28 g/L) , pH 9, Temp: 25 °C
Mass Solubility : Soluble (28 g/L) , pH 10, Temp: 25 °C
Mass Solubility : Soluble (28 g/L) , Unbuffered Water pH 8.39, Temp: 25 °C
Key value for chemical safety assessment
- Water solubility:
- 28 g/L
- at the temperature of:
- 25 °C
Additional information
The result "Soluble (28 g/L) , Unbuffered Water pH 8.39, Temp: 25 °C" was chosen since unbuffered water is the most relevant medium for risk assessment. Furthermore, all available values lead to the conclusion that the substance is very soluble in water, i.e. >10000 mg/L, which is the most relevant information for further risk assessment, and can be regarded as valid due to the consistency of the available data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
