Reaction mass of 1,2-dichloropropane and 3-chloropropene and 3,3-dichloropropene

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

October 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study performed according to relevant tests guidelines under GLP conditions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2010

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Test material

Reference

Name:

Unnamed

Type:

Constituent

Type:

Constituent

Type:

Constituent

Details on test material:

Identification 1,2-Dichloropropane 75
Molecular formula C3H6Cl2
Molecular weight 112.99
CAS Number 78-87-5
Description Clear grey liquid (determined at NOTOX)
Batch RBA100720A (taken from label)
Purity CAS Number
>=65 - <= 80% 1,2-Dichloropropane 78-87-5
>= 8 - <= 20% 2,3-Dichloropropene 78-88-6
>=10 - <= 13% 1,1-Dichloropropene 563-58-6
>= 9 - <= 18% 1,3-Dichloropropene 542-75-6
>= 1 - <= 3% 3-Chloropropene 107-05-1
<= 0.3% Benzene 71-43-2
Test substance storage In refrigerator (2-8°C) protected from light
Stability under storage conditions Stable
Expiry date 23 July 2011 (allocated by NOTOX, 1 year after receipt of the test substance)

Study specific test substance information:
Test substance handling Use amber-coloured glassware or wrap container in tin-foil.

Results and discussion

Water solubility

Water solubility:

1.88 g/L

Temp.:

20 °C

pH:

>= 2.5 - <= 2.8

Details on results:

Preliminary test:
The content of test substance dissolved in the water sample was 2.72 g/l.

Main study:
The results for the samples taken at 24, 48 and 72 hours are given in Table 8.

With the 72-hour measurement a lower value for the analysed concentration was obtained, but with the different time points of 24, 48 and 72 hours no tendency to decreased values was found i.e. the 24- and 48- hour measurements were similar and had a maximum difference of < 15%. According to the guidelines, the water solubility of the test substance is given as the mean value of the 24- and 48-hour measurements.

A small response at the retention time of the test substance was detected in the pretreated sample from the blank water mixture. The response derived from the double distilled water applied. The content of the blank sample to the water solubility of the test substance was 2.5%. It was considered that the response did not affect the water solubility of the test substance.

Any other information on results incl. tables

Table 8           Main study - water solubility of the test substance

Stirring time [hours]	Analysed concentration [g/l]	Mean [g/l]	MD [%]	pH
24	1.88	1.88^1	0.83^1	2.8
48	1.87			2.6
72	0.895			2.5

¹          Obtained with the 24- and 48-hour measurements.

Applicant's summary and conclusion

Conclusions:

Interpretation of results (migrated information): soluble (1000-10000 mg/L)
The flask method was chosen for the determination of the water solubility of the reaction mass containing mainly 1,2-Dichloropropane.

The water solubility of the test substance at 20°C was 1.88 g/l. The pH of the aqueous samples was 2.5 – 2.8.