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Diss Factsheets
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EC number: 204-661-8 | CAS number: 123-91-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish: With high probability acutely not harmful to fish.
Key study:OECD 204 prolonged study, Oryzias latipes (NITE, J-Check database, Japan, data published)
- 21-d LC50 > 100 mg/L (nom., analytically verified)
Supp. Study:No guideline followed, method by Dawson, saltwater, Menidia beryllina (Dawson, 1975, data published)
- 96-h LC50 =6700 mg/L (nom.)
Supp. Study:-No guideline followed, special acute fish toxicity test system by the Center for Lake Superior Environmental Studies, University of Wisconsin-Superior, Pimephales promelas (Geiger, 1990, Test 1, 2, rep. no.: 0-9614968-5-1).
96-h LC50 = 9850 mg/L (nom., analytically verified, Test 1)
96-h LC50 = 10800 mg/L (nom., analytically verified, Test 2)
Supp. Study: similar to OECD 203, Pimephales promelas (Dow Chemical, TSCAT, 1989, rep. no.: ES-DR-0000-9529-4),
96-h LC50 = 13000 mg/L (nom., analytically verified)
Long-term toxicity data to fish:
Key study: similar OECD 210, Pimephales promelas (Dow Chemical, TSCAT, 1989, rep. no.: ES-DR-0000-9529-4):
32-d NOEC = 145 mg/L (measured initial, in agreement with the nominal concentrations)
Short term toxicity to aquatic invertebrates:With high probability acutely not harmful to aquatic invertebrates.
Key study: OECD 202, Daphnia magna (NITE, J-Check database, Japan, data published):
48-h EC50 > 1000 mg/L (nom., analytically verified)
Long-term toxicity to aquatic invertebrates:
Key study: OECD 2011, Daphnia magna (NITE, J-CHECK databank, published data):
21-d NOEC = 1000 mg/L (nominal)
Other information:
Method 1002.0 (EPA 1989), Ceriodaphnia dubia (TSCAT, 1989, rep. no.: OTS0516624-6):
NOEC =625 mg/L (measured)
Toxicity to aquatic algae and cyanobacteria: With high probability acutely not harmful to aquatic algae.
Key study:OECD 201, Desmodesmus subspicatus (NITE, J-CHECK databank, published data, 2016) :
72-h ErC50 > 1000 mg/L (nom., analytically verified)
72-h NOErC = 580 mg/L (nom., analytically verified)
Supp. Study:ISO 8692 (Fresh Water Algal Growth Inhibition Test), Scenedesmus quadricauda
- Bringmann&Kühn, 1977
8-d ErC5 = 5600 mg/L (nom.)
- Bringmann&Kühn, 1978
8-d EbC5 = 575 mg/L (nom.)
Toxicity to aquatic microorganisms: The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
Key study: Bringmann&Kühn, DIN 38412-8 Pseudomonas putida, 1977:
16-h ErC5 = 2700 mg/L (nominal)
Supp. study: ISO 8192, Activated sludge, industrial (BASF AG, 1979, report no.: 760):
30-min EC10 > 2000 mg/L (nominal)
Conclusion: Based on the available experimental data for the substance is considered to be with high probability acutely not harmful to aquatic organisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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