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Diss Factsheets
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EC number: 201-081-7 | CAS number: 78-08-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment. Toxicity report giving very brief summary of this and other studies.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 972
- Report date:
- 1972
Materials and methods
- Principles of method if other than guideline:
- No guideline mentioned. Similar to Inhalation Hazard Test described as an Annex to OECD 403. Exposure to atmosphere said to be saturated with vapour for 7 h.
- GLP compliance:
- no
- Test type:
- standard acute method
Test material
- Reference substance name:
- Triethoxy(vinyl)silane
- EC Number:
- 201-081-7
- EC Name:
- Triethoxy(vinyl)silane
- Cas Number:
- 78-08-0
- Molecular formula:
- C8H18O3Si
- IUPAC Name:
- triethoxy(vinyl)silane
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- not specified
- Vehicle:
- other: unchanged (no vehicle)
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 7 h
- Concentrations:
- Exposure to saturated atmosphere at room temperature (not further specified), said to be approx. 2300 ppm vapour.
- No. of animals per sex per dose:
- Not stated
- Control animals:
- not specified
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LC0
- Effect level:
- > 2 300 ppm
- Based on:
- other: saturated vapour
- Exp. duration:
- 7 h
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- > 2 300 ppm
- Based on:
- other: saturated vapour
- Exp. duration:
- 7 h
- Sex:
- not specified
- Dose descriptor:
- LC0
- Effect level:
- > 17 876 mg/m³ air
- Based on:
- other: a molecular weight of 190.3 g/mol at 25°C
- Exp. duration:
- 7 h
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- > 17 876 mg/m³ air
- Based on:
- other: a molecular weight of 190.3 g/mol at 25°C
- Exp. duration:
- 7 h
Any other information on results incl. tables
No deaths reported. No details of observation period, if any. Moderate diureses reported in an unstated number but no other observations.
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- A very limited summary of an unspecified study, without guideline or GLP compliance (reliability score 4), recorded no deaths in rats from exposure to approx. 2300 ppm vapour. (This reviewer notes this value to be equivalent to around 17876 mg/m³ at 25°C, based on a molecular weight of 190.3 g/mol)
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