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EC number: 410-070-8 | CAS number: 141880-36-6 ACID RED HT 3728; ERIONYL RED HT 3728
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 July 1992 to 14 October 1992
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Deviations:
- yes
- Remarks:
- Deion. water instead of dest. water for the stocksolution; 4 instead of 5 test concentrations; test temperature was 22.6 °C instead of 20 ± 2 °C
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Code number: FAT45155/B
Batch number: TV1
Appearance: solid
Solubility: ~100g/l (in water) [estimation]
Storage: room temperature + light protected
Expiration date: 15.5.1997 - Analytical monitoring:
- no
- Details on sampling:
- no data
- Vehicle:
- no
- Details on test solutions:
- Test concentrations: 320, 100, 32 and 10 mg/l of the test substance; 32, 10 and 3.2 mg/l of the reference substance
- Test organisms (species):
- activated sludge
- Details on inoculum:
- organism: activated sludge of a communal sewage treatment plant (ARA-Pro Pheno Basel)
sludge pretreatment: 3 times washing with tap water and addition of synthenic sewage (a day before the main test)
pH of sludge: 6.6 before the start of the experiment - Test type:
- static
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 3 h
- Hardness:
- no data
- Test temperature:
- Temperature: 22.6 °C
- pH:
- 7.3-7.7
- Dissolved oxygen:
- not applicable
- Salinity:
- no data
- Nominal and measured concentrations:
- Test concentrations 320,100, 32 and 10 mg/l of the test substance
32,10 and 3.2 mg/l of the reference substance - Details on test conditions:
- Sludge dry weight: 1.56 g/l
Test volume: 100 ml
Test duration: 3 h
Estimation technique: O2 - consumption, measured with an oxygen sensitive electrode system: OXI DIGI 530 (SAV : 00 109)
Aeration: 0.1 - 0.2 l/min by pasteur-pipette - Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorophenol (Merck 821768)
- Duration:
- 3 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 320 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Results with reference substance (positive control):
- The IC50 of the reference substance 3,5-Dichlorophenol : 10.5 mg/l.
- Reported statistics and error estimates:
- IC50: The respiration rate of each test concentration was calculated as a percentage of the mean of the two control respiration rates. The results were plotted on a logarithmic (concentration)/normal (% inhibition) graph.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The IC50 (3 h) of FAT 45155/B is > 320 mg/l.
- Executive summary:
A GLP-compliant toxicity study of FAT 45'155/B to activated sludge was determined in a 3-h respiration inhibition test according to the OECD Guideline No. 209. The test substance concentrations tested were 320,100, 32 and 10 mg/l. The reference substance 3,5-Dichlorophenol was tested in concentrations of 32,10 and 3.2 mg/l. Based on the study results, IC50 of FAT-45155/B is >320 mg/l while the reference substance is 10.5 mg/l.
Reference
Description of key information
The IC50 of test substance is >320 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 320 mg/L
Additional information
A GLP-compliant toxicity study of FAT 45155/B to activated sludge was determined in a 3-h respiration inhibition test according to the OECD Guideline No. 209. The test substance concentrations tested were 320,100, 32 and 10 mg/l. The reference substance 3,5-Dichlorophenol was tested in concentrations of 32,10 and 3.2 mg/l. Based on the study results, IC50 of FAT 45155/B is >320 mg/l while the reference substance is 10.5 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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